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Effect of Indoor Air Quality of Day Care Centers in Children with Different Predisposition for Asthma

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dc.contributor.authorCarreiro-Martins, P
dc.contributor.authorPapoila, AL
dc.contributor.authorCaires, I
dc.contributor.authorAzevedo, S
dc.contributor.authorCano, MM
dc.contributor.authorVirella, D
dc.contributor.authorLeiria-Pinto, P
dc.contributor.authorTeixeira, JP
dc.contributor.authorRosado-Pinto, J
dc.contributor.authorAnnesi-Maesano, I
dc.contributor.authorNeuparth, N
dc.date.accessioned2017-11-14T14:54:32Z
dc.date.available2017-11-14T14:54:32Z
dc.date.issued2016
dc.description.abstractScarce information is available about the relationships between indoor air quality (IAQ) at day care centers (DCC), the estimated predisposition for asthma, and the actual wheezing susceptibility. METHODS: In the Phase II of ENVIRH study, 19 DCC were recruited after cluster analysis. Children were evaluated firstly using the ISAAC questionnaire and later by a follow-up questionnaire about recent wheezing. A positive asthma predictive index (API) was considered as predisposition for asthma. Every DCC was audited for IAQ and monitored for chemical and biologic contaminants. RESULTS: We included 1191 children, with a median age of 43 (P25 -P75 : 25-58) months. Considering the overall sample, in the first questionnaire, associations were found between CO2 concentration (increments of 200 ppm) and diagnosis of asthma (OR: 1.10; 95% CI: 1.00-1.20). Each increment of 100 μg/m(3) of total volatile organic compounds (TVOC) and 1 μg of Der p1/g of dust were associated with wheezing in the previous 12 months (OR: 1.06; 95% CI: 1.01-1.11 and OR: 1.06; 95% CI: 0.99-1.12, respectively). In the follow-up questionnaire, TVOC were again associated with wheezing (OR: 1.05; 95% CI: 1.00-1.11). Children exposed to fungal concentration above the 75th percentile had also higher odds of wheezing at follow-up. TVOC were associated with wheezing in children with either negative or positive API.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPediatr Allergy Immunol. 2016 May;27(3):299-306pt_PT
dc.identifier.doi10.1111/pai.12521pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2801
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherJohn Wiley and Sonspt_PT
dc.subjectAir Pollution, Indoorpt_PT
dc.subjectAsthmapt_PT
dc.subjectChild, Preschoolpt_PT
dc.subjectDisease Susceptibilitypt_PT
dc.subjectFemalept_PT
dc.subjectFollow-Up Studiespt_PT
dc.subjectHumanspt_PT
dc.subjectMalept_PT
dc.subjectRespiratory Soundspt_PT
dc.subjectRisk Factorspt_PT
dc.subjectSurveys and Questionnairespt_PT
dc.subjectChild Day Care Centerspt_PT
dc.subjectHDE ALERpt_PT
dc.subjectHDE CINVpt_PT
dc.titleEffect of Indoor Air Quality of Day Care Centers in Children with Different Predisposition for Asthmapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage306pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage299pt_PT
oaire.citation.volume27pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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