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Comparison of Cerebral Perfusion in Perimesencephalic Subarachnoid Hemorrhage and Aneurysmal Subarachnoid Hemorrhage

2018Journal article Open access
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dc.contributor.authorFragata, I
dc.contributor.authorCanto-Moreira, N
dc.contributor.authorCanhão, P
dc.date.accessioned2021-08-13T12:09:12Z
dc.date.available2021-08-13T12:09:12Z
dc.date.issued2018
dc.description.abstractPurpose: Perimesencephalic hemorrhage (PMH) is a benign subtype of nonaneurysmal subarachnoid hemorrhage (SAH). We aimed to investigate if cerebral perfusion in PMH is less affected than in aneurysmal SAH (aSAH). Methods: From a prospective cohort of 80 patients with spontaneous SAH, we included PMH patients (n = 15) and selected aSAH patients (n = 39) with similar clinical grade at admission (World Federation of Neurosurgeons Scale-WFNS I/II). Computed tomography (CT) perfusion was performed at < 72 h and/or at 8-10 days. Cerebral perfusion parameter values were compared between groups with nonparametric tests. Subgroup analyses compared PMH and aSAH patients stratified according to aneurysmal location (anterior or posterior circulation) and blood burden (Fisher grade). Results: At < 72 h, no significant differences in perfusion parameters were found between PMH and aSAH patients. At 8-10 days, PMH patients had lower MTT than aSAH patients, and a trend for higher CBF. PMH patients had higher CBF and CBV at < 72 h when compared to posterior circulation aSAH patients. When compared to aSAH patients with similar blood burden, PMH patients had higher CBF and lower MTT at < 72 h, and lower MTT at 8-10 days. Conclusion: PMH patients had better cerebral perfusion compared to patients with aSAH, particularly during the vasospasm time window. After stratifying for the amount of blood, PMH patients also had better cerebral perfusion in the first 72 h after SAH. These results are in line with the better clinical presentation and prognosis of PMH, and possibly with a different etiology.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNeuroradiology. 2018 Jun;60(6):609-616.pt_PT
dc.identifier.doi10.1007/s00234-018-1997-1.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3830
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.subjectHSJ NRADpt_PT
dc.subjectAdultpt_PT
dc.subjectAgedpt_PT
dc.subjectAneurysm, Ruptured / complicationspt_PT
dc.subjectAged, 80 and overpt_PT
dc.subjectAneurysm, Ruptured / diagnostic imagingpt_PT
dc.subjectCerebral Angiographypt_PT
dc.subjectCerebrovascular Circulationpt_PT
dc.subjectContrast Mediapt_PT
dc.subjectFemalept_PT
dc.subjectMalept_PT
dc.subjectHumanspt_PT
dc.subjectIntracranial Aneurysm / complicationspt_PT
dc.subjectIntracranial Aneurysm / diagnostic imagingpt_PT
dc.subjectMiddle Agedpt_PT
dc.subjectIohexol / analogs & derivativespt_PT
dc.subjectProspective Studiespt_PT
dc.subjectSubarachnoid Hemorrhage / diagnostic imagingpt_PT
dc.subjectSubarachnoid Hemorrhage / etiologypt_PT
dc.subjectTomography, X-Ray Computed / methodspt_PT
dc.titleComparison of Cerebral Perfusion in Perimesencephalic Subarachnoid Hemorrhage and Aneurysmal Subarachnoid Hemorrhagept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage616pt_PT
oaire.citation.startPage609pt_PT
oaire.citation.titleNeuroradiologypt_PT
oaire.citation.volume60pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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