Publication
Risk Factors for Latex Sensitization in Children with Spina Bifida
| dc.contributor.author | Pires, G | |
| dc.contributor.author | Morais-Almeida, M | |
| dc.contributor.author | Gaspar, A | |
| dc.contributor.author | Godinho, N | |
| dc.contributor.author | Calado, E | |
| dc.contributor.author | Abreu-Nogueira, J | |
| dc.contributor.author | Rosado-Pinto, J | |
| dc.date.accessioned | 2012-12-14T10:37:46Z | |
| dc.date.available | 2012-12-14T10:37:46Z | |
| dc.date.issued | 2002 | |
| dc.description.abstract | Background: Children with spina bifida represent the major risk group for latex sensitization. Purpose: To determine the prevalence of latex sensitization in these children and to identify risk factors. Material and methods: We studied 57 patients with spina bifida. The mean age was 5.6 years and the male/female ratio was 0.8/1. In all patients a questionnaire, skin prick test (SPT) with latex (UCBStallergènes, Lofarma and ALK-Abelló), common aeroallergens and fruits (UCB-Stallergènes) and serum determination of total IgE (AlaSTAT) were performed. Results: The prevalence of latex sensitization was 30 %; only two sensitized children (12 %) had symptoms after exposure. Risk factors for latex sensitization were age 5 years (p = 0.008; OR = 6.0; 95% CI = 1.7-22.1), having at least four previous surgical interventions (p < 0.0001; OR = 18.5; 95% CI = 3.6-94.8), having undergone surgery in the first 3 months of life (p = 0.008; OR = 5.4; 95% CI = 0.7-29.2) and total serum IgE 44 IU/ml (p = 0.03; OR = 3.8; 95 %CI = 1.1-13.1). Multiple logistic regression analysis showed that only a history of four or more surgical interventions (p < 0.0001; OR = 26.3; 95 %CI = 2.9-234.2) and total serum IgE 44 IU/ml (p = 0.02; OR = 8.6; 95% CI = 1.4-53.4) were independently associated with latex sensitization. Sex, family and personal allergic history, hydrocephalus with ventriculoperitoneal shunt, cystourethrograms, intermittent bladder catheterization and atopy were not related to latex sensitization. Conclusions: In children with spina bifida, significant and independent risk factors identified for latex sensitization were multiple interventions and higher levels of total serum IgE. A prospective study will clarify the clinical evolution of assymptomatic children sensitized to latex. | por |
| dc.identifier.citation | Allergol et Immunopathol 2002;30(1):5-13. | por |
| dc.identifier.uri | http://hdl.handle.net/10400.17/880 | |
| dc.language | eng | |
| dc.language.iso | other | por |
| dc.publisher | Elsevier | por |
| dc.subject | Látex | por |
| dc.subject | Espinha Bífida | por |
| dc.subject | Hipersensibilidade | por |
| dc.subject | Criança | por |
| dc.subject | Factores de Risco | por |
| dc.subject | HDE ALER | |
| dc.subject | HDE NEU PED | |
| dc.title | Risk Factors for Latex Sensitization in Children with Spina Bifida | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Espanha | por |
| oaire.citation.endPage | 13 | por |
| oaire.citation.startPage | 5 | por |
| oaire.citation.volume | 30 | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |