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When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use

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Case Rep Nephrol Dialys 2021 241.pdf276 KBAdobe PDF Download

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Tacrolimus is an immunosuppressive drug frequently used in solid organ transplant recipients. This drug has well-documented neuropsychiatric side effects in the literature, although emergence of psychotic symptoms is rare, being only described in a very few case reports. We present a case of a renal transplant recipient with no prior psychiatric history, who developed a severe psychosis secondary to supratherapeutic tacrolimus' blood concentrations. This case highlights the importance of clinical awareness to rare but severe neuropsychiatric effects due to tacrolimus use.

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CHLC PSIQ Psychosis Tacrolimus Neurotoxic Neuropsychiatric Side Effects

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Case Rep Nephrol Dial. 2021 Aug 4;11(2):241-246.

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Karger

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