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Nephrotic Syndrome in a Patient with Metastatic Melanoma: Beyond the Obvious

dc.contributor.authorMessias, A
dc.contributor.authorCalado, J
dc.contributor.authorViana, H
dc.contributor.authorNolasco, F
dc.date.accessioned2021-09-20T14:34:32Z
dc.date.available2021-09-20T14:34:32Z
dc.date.issued2019
dc.description.abstractNephrotic syndrome in a patient with metastatic melanoma can occur in the context of a paraneoplastic glomerulopathy or as a complica tion of treatment. New oncologic immunotherapies, including immune checkpoint inhibitors, have been frequently associated with interstitial nephritis and, in rare cases, with nephrotic syndrome. This article presents the case of a 52 -year -old man diagnosed with metastatic melanoma who was admitted with acute kidney injury and nephrotic syndrome after having started immune checkpoint inhibitors. After investigation, acute kidney injury was attributed to immunotherapy -associated acute interstitial nephritis, and nephrotic syndrome was found to be the result of AA amyloidosis, which is a rare complication of metastatic melanoma.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPort J Nephrol Hypert 2019; 33(4): 252-255pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3851
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSociedade Portuguesa de Nefrologia e Hipertensãopt_PT
dc.subjectHCC NEFpt_PT
dc.subjectAmyloidosispt_PT
dc.subjectImmunotherapypt_PT
dc.subjectMelanomapt_PT
dc.subjectNephritispt_PT
dc.titleNephrotic Syndrome in a Patient with Metastatic Melanoma: Beyond the Obviouspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage255pt_PT
oaire.citation.startPage252pt_PT
oaire.citation.titlePortuguese Journal of Nephrology and Hypertensionpt_PT
oaire.citation.volume33pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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