Mineral and Bone Disease (MBD) on a Kidney Transplant Patient

A 50-year-old post-menopausal recipient of a kidney allograft with bone pain, osteoporosis, persistent hypercalcaemia and elevated parathormone (PTH) levels, despite a satisfactory graft function, was treated with bisphosphonates and cinacalcet starting, respectively, 5 and 6 months after renal transplantation (RT). Sixteen months after treatment, there was improvement of bone mineral density (BMD) measured by dualenergy X-ray absorptiometry (DEXA). A bone biopsy was taken, unveiling a surprising and worrisome result. Post-RT bone disease is different from classic CKD-MBD and should be managed distinctly, including, in some difficult cases, an invasive evaluation through the performance of a bone biopsy, as suggested in the KDIGO guidelines.

Keywords

HCC NEF Biópsia Hipercalcemia Transplantação de Rim Osteoporose

URI

http://hdl.handle.net/10400.17/1794

Citation

Port J Nephrol Hypert 2014; 28(1): 69-75

Publisher

Sociedade Portuguesa de Nefrologia e Hipertensão

Collections

NEF - Artigos

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