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Twelve Years of Kawasaki Disease in Portugal: Epidemiology in Hospitalized Children

dc.contributor.authorPinto, FF
dc.contributor.authorLaranjo, S
dc.contributor.authorMota Carmo, M
dc.contributor.authorBrito, MJ
dc.contributor.authorCruz Ferreira, R
dc.date.accessioned2019-04-08T09:30:22Z
dc.date.available2019-04-08T09:30:22Z
dc.date.issued2017
dc.description.abstractKawasaki disease (KD) is the leading cause of acquired heart disease in developed countries. Reported incidences vary worldwide but incidence of KD has not been established in Portugal. The aims of the study were to describe the epidemiologic characteristics and estimate incidence rates of KD among hospitalized children in Portugal. METHODS: This study was a descriptive, population-based study, which used hospital discharge records of patients <20 years of age diagnosed with KD from the Hospital Register database for 2000-2011. Incidence rates were calculated using the number of KD patients and corresponding National census data. RESULTS: There were 533 hospitalizations of 470 patients with KD as the primary diagnosis in Portugal, 63 hospitalizations were transfers of patients between hospitals and there were no relapses. The mean age at admission was 2.8 years, with male predominance (male-to-female ratio: 1.6:1). Children <5 years and infants <1 year represented 83% and 23% of all the patients admitted, respectively. Mean annual incidence was 6.5 per 100,000 children <5 years, 4.5 per 100,000 infants <1 year and 7.8 per 100,000 infants 1-4 years. We found considerable differences between national territorial regions, with majority of cases in most dense regions. The mean length of hospital stay was 9 days, and the incidence peaked in spring (35%) and spring/winter (63%). Coronary aneurysms were reported in 8.5% of patients with a higher male-to-female ratio (3.4:1) and a lower mean age (1.93 years). Reported mortality was 0.4%. CONCLUSIONS: This is the first large-scale epidemiologic study of KD in Portugal. The highest incidences occurred among male children 1-4 years of age and in spring/winter.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPediatr Infect Dis J. 2017 Apr;36(4):364-368pt_PT
dc.identifier.doi10.1097/INF.0000000000001444pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3233
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWolters Kluwerpt_PT
dc.subjectChild, Preschoolpt_PT
dc.subjectCoronary Aneurysmpt_PT
dc.subjectFemalept_PT
dc.subjectHumanspt_PT
dc.subjectIncidencept_PT
dc.subjectLength of Staypt_PT
dc.subjectMalept_PT
dc.subjectMucocutaneous Lymph Node Syndromept_PT
dc.subjectPortugalpt_PT
dc.subjectRetrospective Studiespt_PT
dc.subjectHDE INF PEDpt_PT
dc.subjectHDE CAR PEDpt_PT
dc.titleTwelve Years of Kawasaki Disease in Portugal: Epidemiology in Hospitalized Childrenpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage368pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage364-368pt_PT
oaire.citation.volume36pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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