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Outcomes and Differences by Occluded Vessel after Endovascular Thrombectomy for Isolated Medium Vessel Occlusions

2024-07Journal article Open access
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datacite.subject.fosCiências Médicas
dc.contributor.authorMatsukawa, Hidetoshi
dc.contributor.authorUchida, Kazutaka
dc.contributor.authorCunningham, Conor
dc.contributor.authorSowlat, Mohammad-Mahdi
dc.contributor.authorElawady, Sameh Samir
dc.contributor.authorMaier, Ilko
dc.contributor.authorJabbour, Pascal
dc.contributor.authorKim, Joon-Tae
dc.contributor.authorWolfe, Stacey Quintero
dc.contributor.authorRai, Ansaar
dc.contributor.authorStarke, Robert
dc.contributor.authorPsychogios, Marios-Nikos
dc.contributor.authorShaban, Amir
dc.contributor.authorArthur, Adam
dc.contributor.authorCuellar, Hugo
dc.contributor.authorHoward, Brian
dc.contributor.authorAlawieh, Ali
dc.contributor.authorRomano, Daniele
dc.contributor.authorTanweer, Omar
dc.contributor.authorMascitelli, Justin
dc.contributor.authorFragata, Isabel
dc.contributor.authorPolifka, Adam
dc.contributor.authorOsbun, Joshua
dc.contributor.authorCrosa, Roberto
dc.contributor.authorMatouk, Charles
dc.contributor.authorPark, Min
dc.contributor.authorBrinjikji, Waleed
dc.contributor.authorMoss, Mark
dc.contributor.authorWilliamson, Richard
dc.contributor.authorNavia, Pedro
dc.contributor.authorKan, Peter
dc.contributor.authorLeacy, Reade
dc.contributor.authorChowdhry, Shakeel
dc.contributor.authorEzzeldin, Mohamad
dc.contributor.authorSpiotta, Alejandro
dc.contributor.authorLevitt, Michael
dc.contributor.authorYoshimura, Shinichi
dc.contributor.authorStroke Thrombectomy and Aneurysm Registry (STAR) Collaborators
dc.contributor.editorElsevier
dc.date.accessioned2025-02-14T16:18:19Z
dc.date.available2025-02-14T16:18:19Z
dc.date.issued2024-07
dc.description.abstractBackground: The outcomes of endovascular thrombectomy (EVT) for medium vessel occlusions (MeVOs) of specific vascular territories remain unknown. We aimed to investigate EVT outcomes by MeVO locations using the data from an ongoing international multicenter registry. Methods: Patients with isolated MeVO who underwent EVT between January 2013 and December 2022 were retrospectively analyzed. Isolated MeVO was defined as an occlusion of the A2 or A3 (A2/A3), M2 or M3, and P2 or P3 (P2/P3). Outcomes included a 90-day modified Rankin score (mRS) of 0-2, successful recanalization (modified Thrombolysis in Cerebral Infarction score ≥ 2b), early neurological deterioration (END) or improvement (ENI), and 90-day mortality. END was defined as a worsening of ≥4 points from the baseline National Institutes of Health Stroke Scale (NIHSS) score within 24 h of EVT, while ENI was defined as an improvement of ≥4 points from the baseline NIHSS score within 24 h of EVT. Results: 1744 MeVOs included. Compared to M2 occlusions (n = 1542, 88.4%), A2/A3 (n = 36, 2.1%) occlusions had lower odds of 90-day mRS 0-2 (adjusted odds ratio [aOR] 0.30, 95% confidence interval [CI] 0.11-0.80), and P2/P3 occlusions (n = 49, 2.8%) had lower odds of successful recanalization (aOR 0.19, 95% CI 0.07-0.50), and higher odds of END (aOR 3.53, 95% CI 1.35-9.25). Other outcomes showed no significant differences. Conclusions: A2/A3 occlusions were more likely to have worse outcomes compared to M2 occlusions after EVT for patients with isolated MeVOs.eng
dc.identifier.citationJ Neurol Sci . 2024 Jul 15:462:123054. doi: 10.1016/j.jns.2024.123054.
dc.identifier.doi10.1016/j.jns.2024.123054
dc.identifier.issn0022-510X
dc.identifier.urihttp://hdl.handle.net/10400.17/5061
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAged
dc.subject80 and over
dc.subjectFemale
dc.subjectMale
dc.subjectHumans
dc.subjectEndovascular Procedures* / methods
dc.subjectMiddle Aged
dc.subjectRegistries
dc.subjectRetrospective Studies
dc.subjectThrombectomy* / methods
dc.titleOutcomes and Differences by Occluded Vessel after Endovascular Thrombectomy for Isolated Medium Vessel Occlusionseng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage123054
oaire.citation.titleJournal of the Neurological Sciences
oaire.citation.volume462
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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