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A Comparison of Very Old Patients Admitted to Intensive Care Unit After Acute Versus Elective Surgery or Intervention

2019Journal article Open access
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dc.contributor.authorJung, C
dc.contributor.authorWernly, B
dc.contributor.authorMuessig, J
dc.contributor.authorKelm, M
dc.contributor.authorBoumendil, A
dc.contributor.authorMorandi, A
dc.contributor.authorAndersen, F
dc.contributor.authorArtigas, A
dc.contributor.authorBertolini, G
dc.contributor.authorCecconi, M
dc.contributor.authorChristensen, S
dc.contributor.authorFaraldi, L
dc.contributor.authorFjølner, J
dc.contributor.authorLichtenauer, M
dc.contributor.authorBruno, R
dc.contributor.authorMarsh, B
dc.contributor.authorMoreno, R
dc.contributor.authorOeyen, S
dc.contributor.authorÖhman, C
dc.contributor.authorPinto, B
dc.contributor.authorSoliman, I
dc.contributor.authorSzczeklik, W
dc.contributor.authorValentin, A
dc.contributor.authorWatson, X
dc.contributor.authorZafeiridis, T
dc.contributor.authorDe Lange, D
dc.contributor.authorGuidet, B
dc.contributor.authorFlaatten, H
dc.contributor.authorVIP1 Study Group
dc.date.accessioned2021-10-06T10:49:34Z
dc.date.available2021-10-06T10:49:34Z
dc.date.issued2019
dc.description.abstractBackground: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (≥80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed. Methods: In total, 5063 VIPs were included in this analysis, 922 were admitted after elective surgery or intervention, 4141 acutely, with 402 after acute surgery. Differences were calculated using Mann-Whitney-U test and Wilcoxon test. Univariate and multivariable logistic regression were used to assess associations with mortality. Results: Compared patients admitted after acute surgery, patients admitted after elective surgery suffered less often from frailty as defined as CFS (28% vs 46%; p < 0.001), evidenced lower SOFA scores (4 ± 5 vs 7 ± 7; p < 0.001). Presence of frailty (CFS >4) was associated with significantly increased mortality both in elective surgery patients (7% vs 12%; p = 0.01), in acute surgery (7% vs 12%; p = 0.02). Conclusions: VIPs admitted to ICU after elective surgery evidenced favorable outcome over patients after acute surgery even after correction for relevant confounders. Frailty might be used to guide clinicians in risk stratification in both patients admitted after elective and acute surgery. Trial registration: NCT03134807. Registered 1st May 2017.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Crit Care. 2019 Aug;52:141-148.pt_PT
dc.identifier.doi10.1016/j.jcrc.2019.04.020.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3864
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectHSJ UCIpt_PT
dc.subjectAcute Diseasept_PT
dc.subjectAged, 80 and overpt_PT
dc.subjectCohort Studiespt_PT
dc.subjectCritical Care / statistics & numerical data*pt_PT
dc.subjectElective Surgical Procedures / mortalitypt_PT
dc.subjectElective Surgical Procedures / statistics & numerical data*pt_PT
dc.subjectFemalept_PT
dc.subjectElective Surgical Procedures / statistics & numerical data*pt_PT
dc.subjectMalept_PT
dc.subjectFrail Elderly / statistics & numerical data*pt_PT
dc.subjectFrailty / mortalitypt_PT
dc.subjectFrailty / surgerypt_PT
dc.subjectHospital Mortalitypt_PT
dc.subjectHospitalization / statistics & numerical data*pt_PT
dc.subjectHumanspt_PT
dc.subjectIntensive Care Units / statistics & numerical datapt_PT
dc.subjectLogistic Modelspt_PT
dc.subjectPostoperative Care / statistics & numerical datapt_PT
dc.subjectProspective Studiespt_PT
dc.subjectWounds and Injuries / mortalitypt_PT
dc.subjectWounds and Injuries / surgerypt_PT
dc.titleA Comparison of Very Old Patients Admitted to Intensive Care Unit After Acute Versus Elective Surgery or Interventionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage148pt_PT
oaire.citation.startPage141pt_PT
oaire.citation.titleJournal of Critical Carept_PT
oaire.citation.volume52pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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