Publication
Macular Edema Secondary to Retinal Vein Occlusion in a Real-Life Setting: a Multicenter, Nationwide, 3-Year Follow-Up Study
| dc.contributor.author | Costa, JV | |
| dc.contributor.author | Moura-Coelho, N | |
| dc.contributor.author | Abreu, AC | |
| dc.contributor.author | Neves, P | |
| dc.contributor.author | Ornelas, M | |
| dc.contributor.author | Furtado, MJ | |
| dc.date.accessioned | 2022-12-29T12:36:36Z | |
| dc.date.available | 2022-12-29T12:36:36Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Purpose: To evaluate the presence of macular edema secondary to retinal vein occlusion (RVO)-both central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO)-3 years after diagnosis in patients who underwent intravitreal therapy and to identify potential prognostic factors and biomarkers of persistent macular edema. Methods: National multicenter, observational, exploratory, retrospective cohort study of 104 consecutive patients with macular edema secondary to RVO diagnosed from January 2014 to December 2015 with minimum 3-year follow-up time. Data analyzed included best-corrected visual acuity (BCVA), clinical and demographic data, and spectral domain optical coherence tomography parameters. Results: At final observation, median baseline central retinal thickness significantly improved from baseline 538 to 290 μm (p < 0.001) and complete macular edema resolution was achieved in 51.0% of patients (56.3% and 42.5% in BRVO and CRVO patients, respectively). BCVA also improved (p < 0.01). Logistic regression analysis revealed a relationship between recurrence of macular edema and disorganization of retinal inner layers (DRIL) at baseline (odds ratio = 2.88; p = 0.013). Conclusion: Good long-term anatomical and functional outcomes are achieved with intravitreal treatments in RVO patients. Anatomical success and visual gains seen in the first year were maintained throughout the entire follow-up, though DRIL is a major risk factor for recurrence. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Graefes Arch Clin Exp Ophthalmol . 2021 Feb;259(2):343-350 | pt_PT |
| dc.identifier.doi | 10.1007/s00417-020-04932-0 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/4340 | |
| dc.language.iso | por | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Springerlink | pt_PT |
| dc.subject | Anti-VEGF | pt_PT |
| dc.subject | Chronic macular edema | pt_PT |
| dc.subject | Disorganization of retinal inner layers; | pt_PT |
| dc.subject | Intravitreal injections | pt_PT |
| dc.subject | Retinal vein occlusion | pt_PT |
| dc.subject | Vision loss | pt_PT |
| dc.subject | HSAC OFT | pt_PT |
| dc.title | Macular Edema Secondary to Retinal Vein Occlusion in a Real-Life Setting: a Multicenter, Nationwide, 3-Year Follow-Up Study | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 350 | pt_PT |
| oaire.citation.issue | 2 | pt_PT |
| oaire.citation.startPage | 343 | pt_PT |
| oaire.citation.title | Graefe's Archive for Clinical and Experimental Ophthalmology | pt_PT |
| oaire.citation.volume | 259 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |