Molecular Characterization of a Rare Analphoid Supernumerary Marker Chromosome Derived from 7q35 → qter: A Case Report

Marques, B; Ferreira, C; Brito, F; Pedro, S; Alves, C; Lourenço, T; Amorim, M; Correia, H

http://hdl.handle.net/10400.17/2610

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
Mol Cytogenet 2016_87.pdf		2.42 MB	Adobe PDF	Download

Send Feedback

Authors

Abstract(s)

Analphoid supernumerary marker chromosomes (aSMC) constitute one of the smallest groups of SMC, and are characterized by a centromeric constriction but no detectable alpha-satellite DNA. These marker chromosomes cannot be properly identified by conventional banding techniques alone, and molecular cytogenetic methods are necessary for a detailed characterization. Analphoid SMC derived from chromosome 7 are extremely rare, with only five cases reported so far.