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Atrial Septal Defects

dc.contributor.authorGeva, T
dc.contributor.authorMartins, JD
dc.contributor.authorWald, R
dc.date.accessioned2014-08-07T14:31:54Z
dc.date.available2014-08-07T14:31:54Z
dc.date.issued2014
dc.description.abstractAtrial septal defects are the third most common type of congenital heart disease. Included in this group of malformations are several types of atrial communications that allow shunting of blood between the systemic and the pulmonary circulations. Most children with isolated atrial septal defects are free of symptoms, but the rates of exercise intolerance, atrial tachyarrhythmias, right ventricular dysfunction, and pulmonary hypertension increase with advancing age and life expectancy is reduced in adults with untreated defects. The risk of development of pulmonary vascular disease, a potentially lethal complication, is higher in female patients and in older adults with untreated defects. Surgical closure is safe and effective and when done before age 25 years is associated with normal life expectancy. Transcatheter closure offers a less invasive alternative for patients with a secundum defect who fulfil anatomical and size criteria. In this Seminar we review the causes, anatomy, pathophysiology, treatment, and outcomes of atrial septal defects in children and adult patients in whom this defect is the primary cardiac anomaly.por
dc.identifier.citationLancet. 2014 May 31;383(9932):1921-32por
dc.identifier.urihttp://hdl.handle.net/10400.17/1886
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.subjectHSM CAR PEDpor
dc.subjectCateterismo Cardíacopor
dc.subjectHemodinâmicapor
dc.subjectGravidezpor
dc.subjectComplicações Cardiovasculares na Gravidezpor
dc.subjectPrognósticopor
dc.subjectFactores de Riscopor
dc.subjectDispositivo para Oclusão Septalpor
dc.subjectResultado de Tratamentopor
dc.subjectDeficiências Auriculares do Septo Cardíacopor
dc.titleAtrial Septal Defectspor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1932por
oaire.citation.startPage1921por
oaire.citation.titleThe Lancetpor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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