Publication
Intrauterine Blood Transfusion for Fetal Anemia Treatment – The Experience of 14 Years of a Prenatal Diagnosis Center in Portugal
| dc.contributor.author | Rijo, C | |
| dc.contributor.author | Cohen, A | |
| dc.contributor.author | Martins, AT | |
| dc.contributor.author | Cruz, J | |
| dc.contributor.author | Queirós, A | |
| dc.contributor.author | Ramos, H | |
| dc.contributor.author | Correia, J | |
| dc.date.accessioned | 2022-07-28T09:24:14Z | |
| dc.date.available | 2022-07-28T09:24:14Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | Overview and aims: Intrauterine blood transfusion (IBT) is an established technique for the treatment of severe fetal anemia, increasing the survival of these fetuses. We aimed to describe the experience of a single center in pregnancies complicated with severe fetal anemia, that underwent IBT. Study design, Population, Methods: A retrospective cohort study was conducted from January 1996 to June 2014. Data were collected from 98 IBT performed in 44 pregnancies. Data included: anemia etiology, gestacional age at IBT, hemoglobin and hematocrit levels, presence of hydrops, number of IBTs, gestacional age at birth, sex and weight. Neonatal data included: number of exchange transfusions, respiratory distress syndrome, sepsis and other complications. Results: The main cause of fetal anemia was anti-D alloimmunization in 79.5% of the cases and the mean gestational age (GA) of the first IBT was 26 weeks. The minimum pre-transfusion hemoglobin was 1.5 g/dL, with an average of 6.4g/dL. The post transfusion hematocrit increased to the desired values in 90% of cases. Nine fetuses (20.5%) had hydrops at diagnosis. We had 4 cases of fetal death, and 40 pregnancies resulted in live births, with mean gestational age of 34.3 weeks, average weight of 2446g and mean hemoglobin of 11g/dL. A cesarean was performed in most cases. The overall survival was 86.4%, since in addition to the four fetal deaths there were two cases of early neonatal death. Fetal hydrops and early GA seemed to be associated with a poorer prognosis. Conclusions: IBT is a safe and effective procedure for the treatment of severe fetal anemia. Vigilance should be done in hospitals with experience to allow timely and proper treatment of this condition. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Acta Obstet Ginecol Port 2016;10(2):102-109 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/4155 | |
| dc.language.iso | por | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Federação das Sociedades Portuguesas de Obstetrícia e Ginecologia | pt_PT |
| dc.subject | Intrauterine blood transfusion | pt_PT |
| dc.subject | Cordocenteses | pt_PT |
| dc.subject | Anemia | pt_PT |
| dc.subject | MAC OBS | pt_PT |
| dc.title | Intrauterine Blood Transfusion for Fetal Anemia Treatment – The Experience of 14 Years of a Prenatal Diagnosis Center in Portugal | pt_PT |
| dc.title.alternative | Transfusão Intra-Uterina para o Tratamento de Anemia Fetal Grave – Experiência de 14 anos de um Centro de Diagnóstico Pré-Natal em Portugal | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 109 | pt_PT |
| oaire.citation.issue | 2 | pt_PT |
| oaire.citation.startPage | 102 | pt_PT |
| oaire.citation.volume | 10 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |