Repository logo
 
Publication

Amniocentesis in HIV Pregnant Women: 16 Years of Experience

2013Journal article Open access
Simple item page
dc.contributor.authorSimões, M
dc.contributor.authorMarques, C
dc.contributor.authorGonçalves, A
dc.contributor.authorPereira, AP
dc.contributor.authorCorreia, J
dc.contributor.authorCastela, J
dc.contributor.authorGuerreiro, C
dc.date.accessioned2014-06-19T14:30:14Z
dc.date.available2014-06-19T14:30:14Z
dc.date.issued2013
dc.description.abstractThe iatrogenic risk of HIV vertical transmission, calculated in initial epidemiologic studies, seemed to counterindicate invasive prenatal diagnosis (PND) procedures. The implementation of highly active antiretroviral therapy (HAART) represented a turning point in PND management, owing to a rapid and effective reduction of maternal viral load (VL). In the present study, we identified cases of vertical transmission in HIV-infected pregnant women who did amniocentesis in the second trimester of pregnancy (n = 27), from 1996 to 2011. We divided our sample into Group A--women under HAART when submitted to amniocentesis (n = 20) and Group B--women without antiretroviral therapy before amniocentesis (n = 7). We had 1 case of vertical transmission in Group B. Preconceptional or early first trimester HIV serology is essential to avoid performing an amniocentesis without antiretroviral therapy or viral suppression. When there is an indication for amniocentesis in an HIV-infected pregnant woman, it should be done if the patient is on HAART and, if possible, when VL is undetectable. Nowadays, with combined first trimester screening test to select pregnancies with high risk of aneuploidies, advanced maternal age is a less frequent indication to perform PND invasive procedures, representing an outstanding gain in prenatal diagnosis of this population.por
dc.identifier.citationInfect Dis Obstet Gynecol. 2013;2013:914272. doi: 10.1155/2013/914272. Epub 2013 Jul 21por
dc.identifier.urihttp://hdl.handle.net/10400.17/1830
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherHindawi Publishing Corporationpor
dc.subjectMAC GINpor
dc.subjectMAC PEDpor
dc.subjectMAC MED MAFpor
dc.subjectAmniocentesis/adverse effectspor
dc.subjectAmniocentesis/methodspor
dc.subjectAmniocentesis/statistics & numerical datapor
dc.subjectAnti-Retroviral Agentspor
dc.subjectAnti-Retroviral Therapy, Highly Activepor
dc.subjectCohort Studiespor
dc.subjectHIV Infectionspor
dc.subjectIatrogenic Diseasepor
dc.subjectInfectious Disease Transmission, Verticalpor
dc.subjectPregnancypor
dc.subjectPregnancy Complications, Infectionspor
dc.subjectPregnancy Trimester, Secondpor
dc.titleAmniocentesis in HIV Pregnant Women: 16 Years of Experiencepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleInfectious Diseases in Obstetrics and Gynecologypor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Inf Dis Obst Gynec 2013.pdf
Size:
562.03 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

GIN - Artigos
MED MAF - Artigos
PED - Artigos