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Percutaneous Treatment of Mitral Valve Regurgitation: Initial Experience with the MitraClip Device

dc.contributor.authorCacela, D
dc.contributor.authorFiarresga, A
dc.contributor.authorBranco, LM
dc.contributor.authorGalrinho, A
dc.contributor.authorRio, P
dc.contributor.authorSelas, M
dc.contributor.authorCruz Ferreira, R
dc.date.accessioned2016-02-04T17:15:46Z
dc.date.available2016-02-04T17:15:46Z
dc.date.issued2015-09
dc.description.abstractINTRODUCTION: Mitral regurgitation (MR) is the most common valvular disease and has recently become the target of a number of percutaneous approaches. The MitraClip is virtually the only device for which there is considerable experience, with more than 20,000 procedures performed worldwide. OBJECTIVE: To describe our initial experience of the percutaneous treatment of MR with the MitraClip device. METHODS: We describe the first six MitraClip cases performed in this institution (mean age 58.5 ± 13.1 years), with functional MR grade 4+ and New York Heart Association (NYHA) heart failure class III or IV (n=3), with a mean follow-up of 290 ± 145 days. RESULTS: Procedural success (MR ≤ 2+) was 100%. Total procedure time was 115.8 ± 23.7 min, with no in-hospital adverse events and discharge between the fourth and eighth day, and consistent improvement in the six-minute walk test (329.8 ± 98.42 vs. 385.33 ± 106.95 m) and in NYHA class (three patients improved by two NYHA classes). During follow-up there were two deaths, in two of the four patients who had been initially considered for heart transplantation. CONCLUSION: In patients with functional MR the MitraClip procedure is safe, with both a high implantation and immediate in-hospital success rate. A longer follow-up suggests that the clinical benefit decreases or disappears completely in patients with more advanced heart disease, namely those denied transplantation or on the heart transplant waiting list.pt_PT
dc.identifier.citationRev Port Cardiol. 2015 Sep;34(9):515-24pt_PT
dc.identifier.doi10.1016/j.repc.2015.04.004pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2381
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSociedade Portuguesa de Cardiologiapt_PT
dc.subjectHSM CARpt_PT
dc.subjectMitral Valve Insufficiency/surgerypt_PT
dc.subjectProstheses and Implantspt_PT
dc.subjectProsthesis Designpt_PT
dc.subjectProsthesis Implantation/methodspt_PT
dc.titlePercutaneous Treatment of Mitral Valve Regurgitation: Initial Experience with the MitraClip Devicept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage524pt_PT
oaire.citation.startPage515pt_PT
oaire.citation.titleRevista Portuguesa de Cardiologiapt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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