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Feasibility of Focal Transcranial DC Polarization with Simultaneous EEG Recording: Preliminary Assessment in Healthy Subjects and Human Epilepsy

dc.contributor.authorFaria, P
dc.contributor.authorFregni, F
dc.contributor.authorSebastião, F
dc.contributor.authorDias, AI
dc.contributor.authorLeal, A
dc.date.accessioned2012-12-13T13:18:58Z
dc.date.available2012-12-13T13:18:58Z
dc.date.issued2012
dc.description.abstractWe aimed to investigate the feasibility of an experimental system for simultaneous transcranial DC stimulation(tDCS) and EEG recording in human epilepsy. We report tolerability of this system in a cross-over controlled trial with 15 healthy subjects and preliminary effects of its use, testing repeated tDCS sessions, in two patients with drug-refractory Continuous Spike-Wave Discharges During Slow Sleep (CSWS). Our system combining continuous recording of the EEG with tDCS allows detailed evaluation of the interictal activity during the entire process. Stimulation with 1 mA was well‐tolerated in both healthy volunteers and patients with refractory epilepsy. The large reduction in interictal epileptiform EEG discharges in the two subjects with epilepsy supports further investigation of tDCS using this combined method of stimulation and monitoring in epilepsy. Continuous monitoring of epileptic activity throughout tDCS improves safety and allows detailed evaluation of epileptic activity changes induced by tDCS in patients.por
dc.identifier.citationEpilepsy Behav. 2012; 25:471-425por
dc.identifier.urihttp://hdl.handle.net/10400.17/875
dc.language.isoengpor
dc.publisherElsevierpor
dc.subjectEEGpor
dc.subjectEpilepsiapor
dc.subjectPolarizaçãopor
dc.subjectTranscranialpor
dc.subjectHDE NEU PED
dc.titleFeasibility of Focal Transcranial DC Polarization with Simultaneous EEG Recording: Preliminary Assessment in Healthy Subjects and Human Epilepsypor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage425por
oaire.citation.startPage417por
oaire.citation.volume25por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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