Repository logo
 
Publication

The COVID-19 Pandemic Affects Seasonality, With Increasing Cases of New-Onset Type 1 Diabetes in Children, From the Worldwide SWEET Registry

2022Journal article Open access
Simple item page
dc.contributor.authorReschke, F
dc.contributor.authorLanzinger, S
dc.contributor.authorHerczeg, V
dc.contributor.authorPrahalad, P
dc.contributor.authorSchiaffini, R
dc.contributor.authorMul, D
dc.contributor.authorClapin, H
dc.contributor.authorZabeen, B
dc.contributor.authorPelicand, J
dc.contributor.authorPhillip, M
dc.contributor.authorLimbert, C
dc.contributor.authorDanne, T
dc.contributor.authorAlonso, GT
dc.contributor.authorRhodes, ET
dc.contributor.authorDavis, E
dc.contributor.authorVeeze, HJ
dc.contributor.authorMaahs, D
dc.contributor.authorCardona-Hernandez, R
dc.contributor.authorSumnik, Z
dc.contributor.authorCorathers, S
dc.contributor.authorBratina, N
dc.contributor.authorDanne, T
dc.contributor.authorGevers, E
dc.contributor.authorImane, Z
dc.contributor.authorPiccini, B
dc.contributor.authorForsander, G
dc.contributor.authorPacaud, D
dc.contributor.authorMaffeis, C
dc.contributor.authorCampbell, F
dc.contributor.authorBonfanti, R
dc.contributor.authorde Sanctis, L
dc.contributor.authorKrone, RE
dc.contributor.authorToth-Heyn, P
dc.contributor.authorWitsch, M
dc.contributor.authorArsanoglu, I
dc.contributor.authorJefferies, C
dc.contributor.authorLandry, A
dc.contributor.authorBeltrand, J
dc.contributor.authorAmed, S
dc.contributor.authorRami-Merhar, B
dc.contributor.authorBarat, P
dc.contributor.authorSzypowska, A
dc.contributor.authorZabeen, B
dc.contributor.authorCasteels, K
dc.contributor.authorSavova, R
dc.contributor.authorCherubini, V
dc.contributor.authorde Bock, M
dc.contributor.authorTodorovic, S
dc.contributor.authorLimbert, C
dc.contributor.authorMoravej, H
dc.contributor.authorPozgaj Sepac, M
dc.contributor.authorMazur, A
dc.contributor.authorGerasimidou-Vazeou, A
dc.contributor.authorIotova, V
dc.contributor.authorO’Riordan, S
dc.contributor.authorChobot, A
dc.contributor.authorHerbst, A
dc.contributor.authorNgwu, U
dc.contributor.authorCody, D
dc.contributor.authorBirkebæk, NH
dc.contributor.authorHanas, R
dc.contributor.authorGoksen, D
dc.contributor.authorSarda, A
dc.contributor.authorChobot, J
dc.contributor.authorMirante, A
dc.contributor.authorRichmond Padilla, E
dc.contributor.authorTsiroukidou, K
dc.contributor.authorSaboo, B
dc.contributor.authorKanaka-Gantenbein, C
dc.contributor.authorSchiaffini, R
dc.contributor.authorFoskett, D
dc.contributor.authorJali, S
dc.contributor.authorVerkauskiene, R
dc.contributor.authorCastro-Correia, C
dc.contributor.authorKumar Guness, P
dc.contributor.authorPelicand, J
dc.contributor.authorCotterill, A
dc.contributor.authorKumari Mohan, M
dc.contributor.authorSpehar Uroic, A
dc.contributor.authorGoss, P
dc.contributor.authorSvensson, J
dc.contributor.authorRamchandani, GD
dc.contributor.authorCoutant, R
dc.contributor.authorMantilla, L
dc.contributor.authorSima, A
dc.contributor.authorHyun Kim, J
dc.contributor.authorGalli-Tsinopoulou, A
dc.contributor.authorRibeiro, R
dc.contributor.authorO’Gorman, C
dc.contributor.authorFonna, H
dc.contributor.authorBratke, H
dc.contributor.authorEl Habashy, S
dc.contributor.authorGokalani, R
dc.contributor.authorScharf Pinto, M
dc.contributor.authorChavda, V
dc.date.accessioned2023-12-29T11:23:19Z
dc.date.available2023-12-29T11:23:19Z
dc.date.issued2022
dc.description.abstractObjective: To analyze whether the coronavirus disease 2019 (COVID-19) pandemic increased the number of cases or impacted seasonality of new-onset type 1 diabetes (T1D) in large pediatric diabetes centers globally. Research design and methods: We analyzed data on 17,280 cases of T1D diagnosed during 2018-2021 from 92 worldwide centers participating in the SWEET registry using hierarchic linear regression models. Results: The average number of new-onset T1D cases per center adjusted for the total number of patients treated at the center per year and stratified by age-groups increased from 11.2 (95% CI 10.1-12.2) in 2018 to 21.7 (20.6-22.8) in 2021 for the youngest age-group, <6 years; from 13.1 (12.2-14.0) in 2018 to 26.7 (25.7-27.7) in 2021 for children ages 6 to <12 years; and from 12.2 (11.5-12.9) to 24.7 (24.0-25.5) for adolescents ages 12-18 years (all P < 0.001). These increases remained within the expected increase with the 95% CI of the regression line. However, in Europe and North America following the lockdown early in 2020, the typical seasonality of more cases during winter season was delayed, with a peak during the summer and autumn months. While the seasonal pattern in Europe returned to prepandemic times in 2021, this was not the case in North America. Compared with 2018-2019 (HbA1c 7.7%), higher average HbA1c levels (2020, 8.1%; 2021, 8.6%; P < 0.001) were present within the first year of T1D during the pandemic. Conclusions: The slope of the rise in pediatric new-onset T1D in SWEET centers remained unchanged during the COVID-19 pandemic, but a change in the seasonality at onset became apparent.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDiabetes Care . 2022 Nov 1;45(11):2594-2601pt_PT
dc.identifier.doi10.2337/dc22-0278pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4770
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherAmerican Diabetes Associationpt_PT
dc.subjectAdolescentpt_PT
dc.subjectCOVID-19pt_PT
dc.subjectChildpt_PT
dc.subjectCommunicable Disease Controlpt_PT
dc.subjectPandemicspt_PT
dc.subjectDiabetes Mellitus, Type 1* / epidemiologypt_PT
dc.subjectGlycated Hemoglobinpt_PT
dc.subjectRegistriespt_PT
dc.subjectHDE END PEDpt_PT
dc.titleThe COVID-19 Pandemic Affects Seasonality, With Increasing Cases of New-Onset Type 1 Diabetes in Children, From the Worldwide SWEET Registrypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2601pt_PT
oaire.citation.issue11pt_PT
oaire.citation.startPage2594pt_PT
oaire.citation.titleDiabetes Carept_PT
oaire.citation.volume45pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Diabetes Care 2022_2594.pdf
Size:
6.3 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

END PED - Artigos