Publication
Brain Natriuretic Peptide Levels Predict Morbidity and Mortality in Haemodialysis Patients
| dc.contributor.author | Matias, P | |
| dc.contributor.author | Jorge, C | |
| dc.contributor.author | Aires, I | |
| dc.contributor.author | Lage, H | |
| dc.contributor.author | Gil, C | |
| dc.contributor.author | Gomes, F | |
| dc.contributor.author | Arranhado, E | |
| dc.contributor.author | Ferreira, A | |
| dc.date.accessioned | 2014-05-23T15:36:39Z | |
| dc.date.available | 2014-05-23T15:36:39Z | |
| dc.date.issued | 2009 | |
| dc.description.abstract | Background: Brain natriuretic peptide is a predictor of mortality in multiple cardiovascular diseases but its value in patients with chronic kidney disease is still a matter of debate. Patients and methods: We studied 48 haemodialysis patients with mean age 70.0±13.9 years,62.5% female, 43.8% diabetics, with a mean haemodialysis time of 38.1±29.3 months. To evaluate the role of brain natriuretic peptide as a prognostic factor in this population we performed a two-session evaluation of pre- and postmid-week haemodialysis plasma brain natriuretic peptide concentrations and correlated them with hospitalisation and overall and cardiovascular mortality over a two-year period. Results: There were no significant variations in pre– and post-haemodialysis plasma brain natriuretic peptide concentrations. Pre- and post-haemodialysis brain natriuretic peptide concentrations were significantly greater in patients who died from all causes(p=0.034 and p=0.001, respectively) and from cardiovascular causes (p=0.043 and p=0.001, respectively). Patients who were hospitalised in the two-year study period also presented greater pre- and posthaemodialysis brain natriuretic peptide concentrations(p=0.03 and p=0.036, respectively). Patients with mean brain natriuretic peptide concentrations ≥ 390 pg/mL showed a significantly lower survival at the end of the two-year study period. Conclusion: Brain natriuretic peptide was a good predictor of morbidity and mortality (overall and cardiovascular) in our population. | por |
| dc.identifier.citation | Port J Nephrol Hypert 2009; 23(3): 249-255 | por |
| dc.identifier.uri | http://hdl.handle.net/10400.17/1803 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Sociedade Portuguesa de Nefrologia | por |
| dc.subject | HCC NEF | por |
| dc.subject | Peptídeo Natriurético Encefálico | por |
| dc.subject | Mortalidade | por |
| dc.subject | Hemodiálise | por |
| dc.title | Brain Natriuretic Peptide Levels Predict Morbidity and Mortality in Haemodialysis Patients | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 255 | por |
| oaire.citation.startPage | 249 | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |