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Gadolinium Toxicity and Treatment

dc.contributor.authorRamalho, J
dc.contributor.authorRamalho, M
dc.contributor.authorJay, M
dc.contributor.authorBurke, L
dc.contributor.authorSemelka, R
dc.date.accessioned2017-06-30T15:04:00Z
dc.date.available2017-06-30T15:04:00Z
dc.date.issued2016-12
dc.description.abstractGadolinium based contrast agents (GBCAs) play an important role in the diagnostic evaluation of many patients. The safety of these agents has been once again questioned after gadolinium deposits were observed and measured in brain and bone of patients with normal renal function. This retention of gadolinium in the human body has been termed "gadolinium storage condition". The long-term and cumulative effects of retained gadolinium in the brain and elsewhere are not as yet understood. Recently, patients who report that they suffer from chronic symptoms secondary to gadolinium exposure and retention created gadolinium-toxicity on-line support groups. Their self-reported symptoms have recently been published. Bone and joint complaints, and skin changes were two of the most common complaints. This condition has been termed "gadolinium deposition disease". In this review we will address gadolinium toxicity disorders, from acute adverse reactions to GBCAs to gadolinium deposition disease, with special emphasis on the latter, as it is the most recently described and least known.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMagn Reson Imaging. 2016 Dec;34(10):1394-1398pt_PT
dc.identifier.doi10.1016/j.mri.2016.09.005pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2716
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectBone Diseasespt_PT
dc.subjectBone and Bonespt_PT
dc.subjectBrainpt_PT
dc.subjectBrain Diseasespt_PT
dc.subjectContrast Mediapt_PT
dc.subjectDrug Hypersensitivitypt_PT
dc.subjectGadoliniumpt_PT
dc.subjectHumanspt_PT
dc.subjectJoint Diseasespt_PT
dc.subjectNephrogenic Fibrosing Dermopathypt_PT
dc.subjectCHLC IMApt_PT
dc.titleGadolinium Toxicity and Treatmentpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1398pt_PT
oaire.citation.issue10pt_PT
oaire.citation.startPage1394pt_PT
oaire.citation.titleMagnetic Resonance Imagingpt_PT
oaire.citation.volume34pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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