Publication
Variation in the Care of Acute Liver Failure: A Survey of Intensive Care Professionals
| dc.contributor.author | Cardoso, FS | |
| dc.contributor.author | Mcphail, MJ | |
| dc.contributor.author | Karvellas, CJ | |
| dc.contributor.author | Fuhrmann, V | |
| dc.contributor.author | Germano, N | |
| dc.contributor.author | Auzinger, G | |
| dc.date.accessioned | 2023-04-12T14:07:56Z | |
| dc.date.available | 2023-04-12T14:07:56Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Introduction: Acute liver failure (ALF) is a rare disease with potentially high mortality. We sought to assess the individual approach to ALF by intensive care unit (ICU) professionals. Methods: Cross-sectional survey of ICU professionals. Web-based survey capturing data on respondents' demographics, characteristics of patients with ALF admitted to ICU, and their management. Results: Among 204 participants from 50 countries, 140 (68.6%) worked in Europe, 146 (71.6%) were intensivists, 142 (69.6%) admitted <25 patients with ALF per year, and 166 (81.8%) reported <25% of patients had paracetamol-related ALF. On patients' outcomes, 126 (75.0%) reported an emergency liver transplantation (ELT) rate <25% and 140 (73.3%) a hospital mortality rate <50%. The approach to ALF in the ICU varied with age, region, level of training, type of hospital, and etiology (prescribing N-acetylcysteine for paracetamol toxicity, triggers for endotracheal intubation, measurement of and strategies for lowering serum ammonia, extracorporeal device deployment, and prophylactic antibiotics). Conclusions: The management of patients with ALF by ICU professionals differed substantially concerning the relevant clinical measures taken. Further education and high-quality research are warranted. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | GE Port J Gastroenterol . 2022;29(1):22-30 | pt_PT |
| dc.identifier.doi | 10.1159/000516672 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/4477 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Karger Publishers | pt_PT |
| dc.subject | Hepatitis | pt_PT |
| dc.subject | Critical care | pt_PT |
| dc.subject | Outcomes | pt_PT |
| dc.subject | Survey | pt_PT |
| dc.subject | HCC UCI | pt_PT |
| dc.title | Variation in the Care of Acute Liver Failure: A Survey of Intensive Care Professionals | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 30 | pt_PT |
| oaire.citation.issue | 1 | pt_PT |
| oaire.citation.startPage | 22 | pt_PT |
| oaire.citation.title | GE - Portuguese Journal of Gastroenterology | pt_PT |
| oaire.citation.volume | 29 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |