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Unilateral Versus Bilateral Prostatic Arterial Embolization for Lower Urinary Tract Symptoms in Patients with Prostate Enlargement

dc.contributor.authorBilhim, T
dc.contributor.authorPisco, JM
dc.contributor.authorRio Tinto, H
dc.contributor.authorFernandes, L
dc.contributor.authorPinheiro, LC
dc.contributor.authorDuarte, M
dc.contributor.authorPereira, J
dc.contributor.authorOliveira, A
dc.contributor.authorGoyri-O'Neill, J
dc.date.accessioned2013-03-27T16:00:48Z
dc.date.available2013-03-27T16:00:48Z
dc.date.issued2013
dc.description.abstractPURPOSE: This study was designed to compare baseline data and clinical outcome between patients with prostate enlargement/benign prostatic hyperplasia (PE/BPH) who underwent unilateral and bilateral prostatic arterial embolization (PAE) for the relief of lower urinary tract symptoms (LUTS). METHODS: This single-center, ambispective cohort study compared 122 consecutive patients (mean age 66.7 years) with unilateral versus bilateral PAE from March 2009 to December 2011. Selective PAE was performed with 100- and 200-μm nonspherical polyvinyl alcohol (PVA) particles by a unilateral femoral approach. RESULTS: Bilateral PAE was performed in 103 (84.4 %) patients (group A). The remaining 19 (15.6 %) patients underwent unilateral PAE (group B). Mean follow-up time was 6.7 months in group A and 7.3 months in group B. Mean prostate volume, PSA, International prostate symptom score/quality of life (IPSS/QoL) and post-void residual volume (PVR) reduction, and peak flow rate (Qmax) improvement were 19.4 mL, 1.68 ng/mL, 11.8/2.0 points, 32.9 mL, and 3.9 mL/s in group A and 11.5 mL, 1.98 ng/mL, 8.9/1.4 points, 53.8 mL, and 4.58 mL/s in group B. Poor clinical outcome was observed in 24.3 % of patients from group A and 47.4 % from group B (p = 0.04). CONCLUSIONS: PAE is a safe and effective technique that can induce 48 % improvement in the IPSS score and a prostate volume reduction of 19 %, with good clinical outcome in up to 75 % of treated patients. Bilateral PAE seems to lead to better clinical results; however, up to 50 % of patients after unilateral PAE may have a good clinical outcome.por
dc.identifier.citationCardiovasc Intervent Radiol. 2013 Apr;36(2):403-11por
dc.identifier.urihttp://hdl.handle.net/10400.17/1191
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSpringerpor
dc.subjectHiperplasia Prostáticapor
dc.subjectHSJ UROpor
dc.subjectSintomas do Sistema Urinário Inferiorpor
dc.subjectAnálise de Variância
dc.subjectAngiografia Digital
dc.subjectArtérias
dc.subjectBiópsia
dc.subjectEstudos de Coorte
dc.subjectEmbolização Terapêutica
dc.subjectArtéria Femoral
dc.subjectModelos Logísticos
dc.subjectÁlcool de Polivinil
dc.subjectPróstata
dc.subjectQualidade de Vida
dc.subjectResultado de Tratamento
dc.titleUnilateral Versus Bilateral Prostatic Arterial Embolization for Lower Urinary Tract Symptoms in Patients with Prostate Enlargementpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage411por
oaire.citation.startPage403por
oaire.citation.titleCardiovascular and Interventional Radiologypor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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