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De Novo Hypertension and Decline of Renal Function in a Young Woman with Systemic Lupus Erythematosus and Antiphospholipid Syndrome

dc.contributor.authorViana, H
dc.contributor.authorFerreira, A
dc.contributor.authorCarvalho, F
dc.contributor.authorBordalo, J
dc.contributor.authorRibeiro Santos, J
dc.date.accessioned2013-02-07T13:29:11Z
dc.date.available2013-02-07T13:29:11Z
dc.date.issued2009
dc.description.abstractAntiphospholipid syndrome nephropathy and lupus nephritis have similar clinical and laboratory manifestations and achieving the accuracy of diagnosis required for correct treatment frequently necessitates a kidney biopsy. We report the case of a 29-year-old woman referred to the nephrology service for de novo hypertension, decline of renal function and proteinuria. She had had systemic lupus erythematosus and antiphospholipid syndrome since the age of 21 and was taking oral anticoagulation. Two weeks later, after treatment of hypertension and achievement of adequate coagulation parameters, a percutaneous renal biopsy was performed. The biopsy revealed chronic lesions of focal cortical atrophy, arterial fibrous intimal hyperplasia and arterial thromboses, which are typical features of antiphospholipid syndrome nephropathy. We describe the clinical manifestations and histopathology of antiphospholipid syndrome nephropathy and review the literature on renal biopsy in patients receiving anticoagulation.por
dc.identifier.citationPort J Nephrol Hypert 2009; 23 (4): 357-361por
dc.identifier.urihttp://hdl.handle.net/10400.17/1023
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Nefrologia e Hipertensãopor
dc.subjectSíndrome Antifosfolipídicopor
dc.subjectBiópsiapor
dc.subjectHipertensãopor
dc.subjectLúpus Eritematoso Sistémicopor
dc.titleDe Novo Hypertension and Decline of Renal Function in a Young Woman with Systemic Lupus Erythematosus and Antiphospholipid Syndromepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage361por
oaire.citation.startPage357por
oaire.citation.titleRevista Portuguesa de Nefrologia e Hipertensãopor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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