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Usefulness of Right Ventricular and Right Atrial Two-Dimensional Speckle Tracking Strain to Predict Late Arrhythmic Events in Adult Patients with Repaired Tetralogy of Fallot

2017-01Journal article Open access
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dc.contributor.authorTimóteo, AT
dc.contributor.authorBranco, LM
dc.contributor.authorRosa, S
dc.contributor.authorRamos, R
dc.contributor.authorAgapito, A
dc.contributor.authorSousa, L
dc.contributor.authorGalrinho, A
dc.contributor.authorOliveira, JA
dc.contributor.authorOliveira, MM
dc.contributor.authorCruz Ferreira, R
dc.date.accessioned2017-01-09T13:20:15Z
dc.date.available2017-01-09T13:20:15Z
dc.date.issued2017-01
dc.description.abstractOBJECTIVE: To determine whether right ventricular and/or atrial speckle tracking strain is associated with previous arrhythmic events in patients with repaired tetralogy of Fallot. METHODS AND RESULTS: We studied right ventricular and atrial strain in 100 consecutive patients with repaired tetralogy of Fallot referred for routine echocardiographic evaluation. Patients were divided into two groups, one with previous documentation of arrhythmias (n=26) and one without arrhythmias, in a median follow-up of 22 years. Patients with arrhythmias were older (p<0.001) and had surgical repair at an older age (p=0.001). They also had significantly reduced right ventricular strain (-14.7±5.5 vs. -16.9±4.0%, p=0.029) and right atrial strain (19.1±7.7% vs. 25.8±11.4%, p=0.001). Neither right ventricular nor right atrial strain were independent predictors of the presence of a history of documented arrhythmias, which was associated with age at correction and with the presence of residual defects. In a subanalysis after excluding 23 patients who had had more than one corrective surgery, right ventricular strain was an independent predictor of the presence of previous arrhythmic events (OR 1.19, 95% CI 1.02-1.38, p=0.025). Right atrial strain was also an independent predictor after adjustment (OR 0.93, 95% CI 0.87-0.99, p=0.029). The ideal cut-off for right ventricular strain was -15.3% and for right atrial strain 23.0%. CONCLUSIONS: Compared with conventional echocardiographic parameters, strain measures of the right heart are associated with the presence of arrhythmic events, and may be useful for risk stratification of patients with repaired tetralogy of Fallot, although a prospective study is required.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRev Port Cardiol. 2017 Jan;36(1):21-29pt_PT
dc.identifier.doi10.1016/j.repc.2016.07.005pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2596
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier Españapt_PT
dc.subjectHSM CARpt_PT
dc.subjectArrhythmias, Cardiac/diagnostic imagingpt_PT
dc.subjectArrhythmias, Cardiac/physiopathologypt_PT
dc.subjectEchocardiographypt_PT
dc.subjectFollow-Up Studies
dc.subjectHeart Ventricles/diagnostic imaging
dc.subjectHeart Ventricles/physiopathology
dc.subjectPostoperative Complications
dc.subjectPredictive Value of Tests
dc.subjectRetrospective Studies
dc.subjectTetralogy of Fallot/surgery
dc.subjectTime Factors
dc.titleUsefulness of Right Ventricular and Right Atrial Two-Dimensional Speckle Tracking Strain to Predict Late Arrhythmic Events in Adult Patients with Repaired Tetralogy of Fallotpt_PT
dc.title.alternativeUtilidade do Strain Bidimensional por Speckle Tracking da Aurícula e Ventrículo Direito para Predizer Arritmias Tardias em Doentes Adultos com Tetralogia de Fallot Corrigidapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage29pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage21pt_PT
oaire.citation.titleRevista Portuguesa de Cardiologiapt_PT
oaire.citation.volume36pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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