Repository logo
 
Publication

Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality

2022-05Journal article Open access
Simple item page
dc.contributor.authorNguyen, T
dc.contributor.authorQureshi, M
dc.contributor.authorKlein, P
dc.contributor.authorYamagami, H
dc.contributor.authorAbdalkader, M
dc.contributor.authorMikulik, R
dc.contributor.authorSathya, A
dc.contributor.authorMansour, O
dc.contributor.authorCzlonkowska, A
dc.contributor.authorLo, H
dc.contributor.authorField, T
dc.contributor.authorCharidimou, A
dc.contributor.authorBanerjee, S
dc.contributor.authorYaghi, S
dc.contributor.authorSiegler, J
dc.contributor.authorSedova, P
dc.contributor.authorKwan, J
dc.contributor.authorAguiar de Sousa, D
dc.contributor.authorDemeestere, J
dc.contributor.authorInoa, V
dc.contributor.authorOmran, S
dc.contributor.authorZhang, L
dc.contributor.authorMichel, P
dc.contributor.authorStrambo, D
dc.contributor.authorMarto, JP
dc.contributor.authorNogueira, R
dc.date.accessioned2023-08-25T14:59:29Z
dc.date.available2023-08-25T14:59:29Z
dc.date.issued2022-05
dc.description.abstractBackground and purpose: Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year. Methods: We conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020). Results: There were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths. Conclusions: During the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Stroke . 2022 May;24(2):256-265.pt_PT
dc.identifier.doi10.5853/jos.2022.00752pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4662
dc.language.isoengpt_PT
dc.publisherKorean Stroke Societypt_PT
dc.subjectHSJ NEUpt_PT
dc.subjectCOVID-19pt_PT
dc.subjectCerebral venous thrombosispt_PT
dc.subjectSARS-CoV-2pt_PT
dc.subjectMortalitypt_PT
dc.subjectStrokept_PT
dc.subjectVaccine-Induced Immune Thrombotic Thrombocytopeniapt_PT
dc.titleGlobal Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortalitypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage265pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage256pt_PT
oaire.citation.titleJournal of Strokept_PT
oaire.citation.volume24pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
J Stroke 2021 256.pdf
Size:
237.13 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

NEU - Artigos