Publication
Serum Fetuin-A Levels Are Associated with Serum Triglycerides Before and 6 Months after Bariatric Surgery
| dc.contributor.author | Verras, CG | |
| dc.contributor.author | Christou, GA | |
| dc.contributor.author | Simos, YV | |
| dc.contributor.author | Ayiomamitis, GD | |
| dc.contributor.author | Melidonis, AJ | |
| dc.contributor.author | Kiortsis, DN | |
| dc.date.accessioned | 2018-03-02T16:33:39Z | |
| dc.date.available | 2018-03-02T16:33:39Z | |
| dc.date.issued | 2017-07 | |
| dc.description.abstract | OBJECTIVE: The elucidation of the changes of fetuin-A in the context of bariatric surgery. DESIGN: Twenty obese patients (8 males, 12 females; body mass index = 42.5±3.4 kg/m2) were studied at baseline and 6 months after bariatric surgery. RESULTS: Serum fetuin-A levels did not differ with regard to the presence of each individual component of the Metabolic Syndrome (MetS) at baseline, except for hypertriglyceridaemia [increased serum fetuin-A levels (p=0.011)]. Circulating fetuin-A was positively correlated with serum triglycerides (TG) (r=0.461, p=0.047) and negatively correlated with serum globulins (r=-0.477, p=0.033) and C-reactive protein (CRP) (r=-0.604, p=0.010), while it independently predicted TG at baseline. Circulating fetuin-A did not change during the 6 months either in the whole population or in the subgroups of patients who were positive for each individual component of MetS at baseline and negative for this component at 6 months of follow-up, except for hypertriglyceridaemia [reduction of serum fetuin-A levels (p=0.046)]. The subgroup of patients with a decrease in circulating fetuin-A during the 6 months was characterized by a smaller reduction of serum globulins (p=0.003) and CRP (p=0.049). The change in serum fetuin-A levels over the 6 months was positively correlated with the change in TG (r=0.592, p=0.006) and negatively correlated with the change in serum globulins (r=-0.523, p=0.018) and CRP (r=-.494, p=0.037). CONCLUSIONS: Circulating fetuin-A predicted serum triglycerides before as well as 6 months after bariatric surgery. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Hormones (Athens). 2017 Jul;16(3):297-305. | pt_PT |
| dc.identifier.doi | 10.14310/horm.2002.1739 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/2929 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | Hellenic Endocrine Society | pt_PT |
| dc.subject | HCC END | pt_PT |
| dc.subject | Adiposity/physiology | pt_PT |
| dc.subject | Bariatric Surgery | pt_PT |
| dc.subject | Body Mass Index | pt_PT |
| dc.subject | Metabolic Syndrome/blood | |
| dc.subject | Obesity, Morbid/blood | |
| dc.subject | Obesity, Morbid/surgery | |
| dc.subject | Postoperative Period | |
| dc.subject | Triglycerides/blood | |
| dc.subject | alpha-2-HS-Glycoprotein/metabolism | |
| dc.title | Serum Fetuin-A Levels Are Associated with Serum Triglycerides Before and 6 Months after Bariatric Surgery | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 305 | pt_PT |
| oaire.citation.issue | 3 | pt_PT |
| oaire.citation.startPage | 297 | pt_PT |
| oaire.citation.title | Hormones (Athens) | pt_PT |
| oaire.citation.volume | 16 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |