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Mandibular Resorption and Vocal Cord Paralysis: a Catastrophic Form of Systemic Sclerosis

2019-02-28Journal article Open access
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dc.contributor.authorMendonça, P
dc.contributor.authorTaulaigo, AV
dc.contributor.authorCaetano, A
dc.contributor.authorMoraes-Fontes, MF
dc.date.accessioned2020-05-22T11:45:01Z
dc.date.available2020-05-22T11:45:01Z
dc.date.issued2019-02-28
dc.description.abstractSudden respiratory distress in association with severe weight loss are unusual features of systemic sclerosis (SSc). We report the case of a 56-year-old Caucasian woman with a 9-year history of a diffuse form of SSc who presented with acute stridor due to vocal cord paralysis and required an emergency tracheostomy. She had sought medical attention only after 4 years of disease onset, presenting with a mask-like face, diffuse skin thickening, acro-osteolysis and severe interstitial lung disease. Even though skin tightness improved after immunosuppressive treatment, several spontaneous facial fractures and episodes of dysphagia and choking occurred in the years that followed. At the time of stridor, she was severely malnourished and a percutaneous endoscopic gastrostomy was required for feeding. Permanent vocal cord damage in combination with severe loco-regional bone resorption resulted in severe disability and impaired nutrition. We hereby highlight the features of SSc for which therapy remains challenging.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBMJ Case Rep . 2019 Feb 28;12(2):e228262pt_PT
dc.identifier.doi10.1136/bcr-2018-228262pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3463
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJ Publishing Grouppt_PT
dc.subjectAntibodies, Monoclonal, Humanizedpt_PT
dc.subjectBone Resorptionpt_PT
dc.subjectCalciumpt_PT
dc.subjectDiagnosis, Differentialpt_PT
dc.subjectDietary Supplementspt_PT
dc.subjectFemalept_PT
dc.subjectHumanspt_PT
dc.subjectMalnutritionpt_PT
dc.subjectMandiblept_PT
dc.subjectMiddle Agedpt_PT
dc.subjectScleroderma, Systemicpt_PT
dc.subjectTomography, X-Ray Computedpt_PT
dc.subjectTracheostomypt_PT
dc.subjectVitamin Dpt_PT
dc.subjectVocal Cord Paralysispt_PT
dc.subjectHCC DAUTOIMpt_PT
dc.subjectHCC IMApt_PT
dc.titleMandibular Resorption and Vocal Cord Paralysis: a Catastrophic Form of Systemic Sclerosispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue2pt_PT
oaire.citation.startPagee228262pt_PT
oaire.citation.titleBMJ Case Reportspt_PT
oaire.citation.volume12pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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