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Amiodarone-Induced Thyrotoxicosis in a Pediatric Patient: A Rare and Demanding Clinical Case

dc.contributor.authorOliveira, S
dc.contributor.authorMarques, B
dc.contributor.authorLaranjo, S
dc.contributor.authorLopes, L
dc.date.accessioned2021-04-29T18:42:10Z
dc.date.available2021-04-29T18:42:10Z
dc.date.issued2019-09-24
dc.description.abstractThyroid dysfunction is one of the most common adverse effects of amiodarone therapy, ranging from subclinical changes to overt clinical thyrotoxicosis (AIT) and/or hypothyroidism. Due to its heterogeneity, AIT lasts as a defiant entity, leading to a thorny treatment course, particularly in pediatrics. AIT can be classified as either type 1, type 2 or mixed form based on its pathophysiology. Differentiating between the main AIT subtypes is quite relevant, since there is specific treatment for both, however, this distinction may be difficult in clinical practice. We describe a rare case of AIT in a pediatric patient, with an uncommon congenital cardiac malformation, that started amiodarone therapy due to paroxysmal supraventricular tachycardia. AIT was reported 26 months after drug onset, with a sudden and explosive emerging. This case highlights the current AIT management challenges on the highdemanding pediatric field pursuing, ultimately, an enhanced patient´s care.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPediatr Rep . 2019 Sep 24;11(3):8166pt_PT
dc.identifier.doi10.4081/pr.2019.8166pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3676
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherPage Presspt_PT
dc.subjectAmiodaronept_PT
dc.subjectThyrotoxicosispt_PT
dc.subjectAdolescentpt_PT
dc.subjectHDE END PEDpt_PT
dc.subjectHSM CAR PEDpt_PT
dc.titleAmiodarone-Induced Thyrotoxicosis in a Pediatric Patient: A Rare and Demanding Clinical Casept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue3pt_PT
oaire.citation.startPage8166pt_PT
oaire.citation.titlePediatric reportspt_PT
oaire.citation.volume11pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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