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Inflammatory Myofibroblastic Tumour of the Common Bile Duct

dc.contributor.authorAlmeida e Sousa, M
dc.contributor.authorCarvalho, A
dc.contributor.authorMega, R
dc.contributor.authorBilhim, T
dc.date.accessioned2023-05-16T09:34:22Z
dc.date.available2023-05-16T09:34:22Z
dc.date.issued2022
dc.description.abstractInflammatory myofibroblastic tumour is a rare entity of indeterminate biological potential with a reduced tendency for recurrence and metastasis. Although it can arise from multiple organs, the bile duct is a very rare site of origin. We report the case of a 75-year-old asymptomatic male with elevated gamma-glutamyl transferase [1575 U/L (12 - 64 U/L)] and alkaline phosphatase [271 U/L (40 - 150 U/L)]. Computed tomography showed a 17 mm hypervascular lesion in the confluence of the right and left hepatic ducts, with bile duct ectasia and right liver lobe atrophy. The patient was initially managed as having a Klatskin tumour and underwent right hepatectomy. Histology showed a spindle cell proliferation with an inflammatory infiltrate of lymphocytes, plasma cells and collagen-rich stroma, consistent with an inflammatory myofibroblastic tumour. He was discharged 30 days after admission, and nine months later remains asymptomatic. His liver function tests have normalized and follow-up tests are unremarkable.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationActa Med Port 2022 Oct;35(10):765-769pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4513
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherCentro Editor Livreiro da Ordem dos Médicospt_PT
dc.subjectBile Duct Neoplasmspt_PT
dc.subjectHepatectomy;pt_PT
dc.subjectHepatic Duct, Commonpt_PT
dc.subjectKlatskin Tumourpt_PT
dc.subjectLiver Function Testspt_PT
dc.subjectIMApt_PT
dc.subjectANPATpt_PT
dc.titleInflammatory Myofibroblastic Tumour of the Common Bile Ductpt_PT
dc.title.alternativeTumor Inflamatório Miofibroblástico da Via Biliar Principalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage769pt_PT
oaire.citation.issue35pt_PT
oaire.citation.startPage765pt_PT
oaire.citation.volume10pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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