Publication
The Prognostic Impact of Renal Failure in Patients with ST-Segment Elevation Acute Myocardial Infarction
| dc.contributor.author | Timóteo, AT | |
| dc.contributor.author | Fiarresga, A | |
| dc.contributor.author | Feliciano, J | |
| dc.contributor.author | Pelicano, NJ | |
| dc.contributor.author | Ferreira, ML | |
| dc.contributor.author | Cruz Ferreira, R | |
| dc.contributor.author | Serra, J | |
| dc.contributor.author | Oliveira, JA | |
| dc.contributor.author | Quininha, J | |
| dc.date.accessioned | 2011-03-30T16:34:09Z | |
| dc.date.available | 2011-03-30T16:34:09Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | INTRODUCTION: Renal insufficiency (RI) is associated with higher morbidity and mortality in patients (P) with coronary artery disease and in P submitted to angioplasty. In ST-segment elevation acute myocardial infarction (STEAMI), this impact has not been well demonstrated. AIM: To evaluate the impact of RI in P with STEAMI. METHODS: We evaluated 160 P admitted with STEAMI, mean age of 62+/-14 years, 76% male. We determined creatinine levels on admission. RI was defined as a level >1.5 mg/dl. Analysis of clinical, electrocardiographic and laboratory variables was performed, in relation to the endpoint defined as the occurrence of death at 30-day follow-up. RESULTS: There were 16 deaths (10%) at 30-day follow-up. P with RI (n=21) were older (68+/-11 vs 61+/-14 years, p<0.001), more often had diabetes (57 vs 24 %, p=0.004) and presented more often with Killip class > or =2 (57 vs 12%, p<0.001). The use of statins (62 vs 83%, p=0.05) and beta-blockers (24 vs 65%, p<0.001) was lower in P with RI. Mortality was higher in RI P (62 vs 2%, p<0.001). The univariate predictors of death were age > or =75 years, diabetes, Killip class > or =2 on admission, RI, non-use of statins and beta-blockers and use of diuretics. In multivariate analysis, independent predictors of death at 30 days were RI (HR 29.6, 95% CI 6.3-139.9, p<0.001) and non-use of beta-blockers (HR 0.13, 95% CI 0.02-1.01, p=0.01). CONCLUSION: In P admitted for STEAMI, the presence of RI was an independent predictor of death at 30 days whereas the usage of beta-blockers was protective. | por |
| dc.identifier.citation | Kardiol Pol. 2005 Oct; 63 (4): 373-8 | por |
| dc.identifier.uri | http://hdl.handle.net/10400.17/37 | |
| dc.language.iso | eng | por |
| dc.publisher | Polish Cardiac Society | por |
| dc.subject | Adulto | por |
| dc.subject | Idoso | por |
| dc.subject | Comorbidade | por |
| dc.subject | Intervalos de Confiança | |
| dc.subject | Creatinina | |
| dc.subject | Electrocardiografia | |
| dc.subject | Sistema de Condução Cardíaco | |
| dc.subject | Falência Renal Crónica | |
| dc.subject | Enfarte do Miocárdio | |
| dc.subject | Razão de Possibilidades | |
| dc.subject | Prognóstico | |
| dc.subject | Estudos Retrospectivos | |
| dc.subject | Análise de Sobrevivência | |
| dc.subject | HSM CAR | |
| dc.title | The Prognostic Impact of Renal Failure in Patients with ST-Segment Elevation Acute Myocardial Infarction | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 378 | por |
| oaire.citation.startPage | 373 | por |
| oaire.citation.title | Kardiologia Polska | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |