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Browsing by Author "Bento, A"

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  • OPTImized Coronary Interventions EXplaIn the BEst CliNical OutcomEs (OPTI-XIENCE) Study. Rationale and Study Design
    Publication . Moreno, R; Bravo Baptista, S; Valencia, J; Gomez-Menchero, A; Bouisset, F; Ruiz-Arroyo, JR; Bento, A; Besutti, M; Jimenez-Valero, S; Rivero-Santana, B; Olhmann, P; Santos, M; Vaquerizo, B; Cuissetm, T; Lemoine, J; Pinar, E; Fiarresga, A; Urbano, C; Marliere, S; Braga, C; Amat-Santos, I; Morgado, G; Sarnago, F; Telleria, M; Van Belle, E; Díaz-Fernandez, J; Caballero Borrego, J; Amabile, N; Meneveau, N
    Introduction: Clinical events may occur after percutaneous coronary intervention (PCI), particularly in complex lesions and complex patients. The optimization of PCI result, using pressure guidewire and intracoronary imaging techniques, may reduce the risk of these events. The hypothesis of the present study is that the clinical outcome of patients with indication of PCI and coronary stent implantation that are at high risk of events can be improved with an unrestricted use of intracoronary tools that allow PCI optimization. Methods and analysis: Observational prospective multicenter international study, with a follow-up of 12 months, including 1064 patients treated with a cobalt‑chromium everolimus-eluting stent. Inclusion criteria include any of the following: Lesion length > 28 mm; Reference vessel diameter < 2.5 mm or > 4.25 mm; Chronic total occlusion; Bifurcation with side branch ≥2.0 mm;Ostial lesion; Left main lesion; In-stent restenosis; >2 lesions stented in the same vessel; Treatment of >2 vessels; Acute myocardial infarction; Renal insufficiency; Left ventricular ejection fraction <30 %; Staged procedure. The control group will be comprised by a similar number of matched patients included in the "extended risk" cohort of the XIENCE V USA study. The primary endpoint will be the 1-year rate of target lesion failure (TLF) (composite of ischemia-driven TLR, myocardial infarction (MI) related to the target vessel, or cardiac death related to the target vessel). Secondary endpoints will include overall mortality, cardiovascular mortality, acute myocardial infarction, TVR, TLR, target vessel failure, and definitive or probable stent thrombosis at 1 year. Implications: The ongoing OPTI-XIENCE study will contribute to the growing evidence supporting the use of intra-coronary imaging techniques for stent optimization in patients with complex coronary lesions.
    2024Journal article Open access Show more
  • Postictal Psychosis: Case Report and Literature Review
    Publication . Regala, J; Lourenço, J; Moniz-Pereira, F; Bento, A
    Postictal psychosis (PIP) is one of the most common types of psychosis in epileptic patients. By virtue of the paucity of research on PIP, its pathophysiology remains not completely understood. Our case report describes a clinical picture of PIP, characterized by pleomorphic features, with neither Schneider's first-rank symptoms nor negative symptoms of schizophrenia, in a longstanding epileptic female patient with a history of nonadherence to antiepileptic treatment and poorly controlled seizures. Additionally, she had previous cognitive impairment and encephalomalacia in the right parietooccipital region as a sequela of a moderate-to-severe traumatic brain injury known to precede the emergence of the epilepsy. In light of our findings, we critically reviewed the current literature on postictal psychoses providing insight into its neurobiological underpinnings.
    2023Journal article Open access Show more