Browsing by Author "Ribeiro, C"
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- Adesão ao Programa "PSIC" - Uma Análise DescritivaPublication . Mesquita Reis, J; Jorge, S; Ferreira, B; Maia, T; Santos, E; Maximiano, J; Ribeiro, C; Fernandes, C; Roquette, TIntrodução: A intervenção preconizada no primeiro episódio psicótico (PEP) engloba o recurso a psicofármacos e a intervenções psicossociais. A adesão à medicação e o cumprimento dos tratamentos psicossociais são essenciais para o sucesso das intervenções. Estima-se que a não adesão à medicação no primeiro ano após o diagnóstico de psicose ocorra em cerca de metade dos doentes, sendo também elevada a taxa de abandono relativa às intervenções psicossociais. Vários estudos têm procurado determinar quais os fatores que contribuem para a não adesão à intervenção. No serviço de Psiquiatria do Hospital Prof. Dr. Fernando Fonseca (HFF) desenvolve-se um protocolo de avaliação e intervenção no PEP, o “PSIC”, o qual visa a avaliação global da sintomatologia e do funcionamento do indivíduo e a aplicação de intervenções específicas. Objetivos: Caraterização do perfil sociodemográfico, clínico e de adesão ao tratamento numa amostra de pacientes com PEP. Métodos: Realizou-se um estudo transversal, cujos dados foram obtidos a partir do preenchimento de um questionário com variáveis sociodemográficas, clínicas e de adesão, relativos aos pacientes referenciados ao “PSIC”, desde inicio de 2014 a 2017. Adicionalmente, analisou-se, retrospectivamente, a adesão à medicação e às intervenções psicossociais. Os dados foram tratados em SPSS®(v10.0.1). Resultados: Da amostra inicial foram elegíveis 28 pacientes. Os pacientes apresentaram bons índices de adesão à medicação, tendencialmente superiores aos existentes na literatura. No que respeita às intervenções psicossociais os resultados encontram-se em conformidade com os encontrados por outros grupos. Não se encontrou associação entre a adesão ao protocolo ou à medicação e o género, ser imigrante, escolaridade e história de consumos. Contudo, encontrou-se uma associação estatisticamente significativa entre a má adesão ao protocolo e a inexistência de atividade laboral à entrada no protocolo (p 0,049*), assim como com a ausência de atividade socio-ocupacional durante o protocolo de intervenção (p 0,036*). Encontrou-se uma associação estatisticamente significativa entre a boa adesão ao protocolo e um envolvimento positivo da família (p 0,046*). Conclusões: O reconhecimento antecipado de fatores de não adesão é essencial na estruturação de intervenções a eles dirigidas (como por exemplo a promoção de intervenção familiar), favorecendo a adesão ao projeto terapêutico e modificando o curso da doença.
- Aracnoidite Adesiva LombarPublication . Ribeiro, C; Reis, FCSpinal arachnoiditis, an inflammatory process involving all three meningeal layers as well as the nerve roots, is a cause of persistent symptoms in 6% to 16% of postoperative patients. Although spinal surgery is the most common antecedent associated with arachnoiditis, multiple causes have been reported, including infection, intrathecal steroids or anesthetic agents, trauma, subarachnoid hemorrhage and ionic myelographic contrast material--both oil soluble and water soluble. In the past, oil-based intrathecal contrast agents (Pantopaque) were associated with arachnoiditis especially when this material was introduced into the thecal sac and mixed with blood. Arachnoiditis is apparently rarely idiopathic. The pathogenesis of spinal arachnoiditis is similar to the repair process of serous membranes, such as the peritoneum, with a negligible inflammatory cellular exudate and a prominent fibrinous exudate. Chronic adhesive arachnoiditis of the lower spine is a myelographic diagnosis. The myelographic findings of arachnoiditis were divided into two types by Jorgensen et al. In type 1, "the empty thecal sac" appearance, there is homogeneous filling of the thecal sac with either absence of or defects involving nerve root sleeve filling. In type 2 arachnoiditis, there are localized or diffuse filling defects within the contrast column. MRI has demonstrated a sensitivity of 92% and a specificity of 100% in the diagnosis of arachnoiditis. The appearance of arachnoiditis on MRI can be assigned to three main groups. The MRI findings in group I are a conglomeration of adherent roots positioned centrally in the thecal sac. Patients in group II show roots peripherally adherent to the meninges--the so called empty sac. MRI findings in group III are a soft tissue mass within the subarachnoid space. It corresponds to the type 2 categorization defined by Jorgensen et al, where as the MRI imaging types I and II correspond to the myelographic type 1.
- Asthma App Use and Interest Among Patients With Asthma: A Multicenter StudyPublication . Jácome, C; Almeida, R; Pereira, AM; Araújo, L; Correia, MA; Pereira, M; Couto, M; Lopes, C; Chaves Loureiro, C; Catarata, MJ; Santos, LM; Ramos, B; Mendes, A; Pedro, E; Cidrais Rodrigues, JC; Oliveira, G; Aguiar, AP; Arrobas, AM; Costa, J; Dias, J; Todo Bom, A; Azevedo, J; Ribeiro, C; Alves, M; Pinto, PL; Neuparth, N; Palhinha, A; Marques, JG; Martins, P; Trincão, D; Neves, A; Todo Bom, F; Santos, M A; Branco, J; Loyoza, C; Costa, A; Silva Neto, A; Silva, D; Vasconcelos, MJ; Teixeira, MF; Ferreira-Magalhães, M; Taborda Barata, L; Carvalhal, C; Santos, N; Sofia Pinto, C; Rodrigues Alves, R; Moreira, AS; Morais Silva, P; Fernandes, R; Ferreira, R; Alves, C; Câmara, R; Ferraz de Oliveira, J; Bordalo, D; Calix, MJ; Marques, A; Nunes, C; Menezes, F; Gomes, R; Almeida Fonseca, J
- Different Electroclinical Manifestations of the Epilepsy Associated with Hamartomas Connecting to the Middle or Posterior HypothalamusPublication . Leal, A; Moreira, A; Robalo, C; Ribeiro, CPURPOSE: The epilepsy associated with hypothalamic hamartomas (HHs) has typical clinical, electrophysiologic, and behavioral manifestations refractory to drug therapy and with unfavorable evolution. It is well known that only sessile lesions produce epilepsy, but no correlation has been established between the different types of sessile hamartomas and the diverse manifestations of the epilepsy. We correlate anatomic details of the hamartoma and the clinical and neurophysiologic manifestations of the associated epilepsy. METHODS: HHs of seven patients with epilepsy (ages 2- 25 years) were classified as to lateralization and connection to the anteroposterior axis of the hypothalamus by using high-resolution brain magnetic resonance imaging. We correlated the anatomic classification with the clinical and neurophysiologic manifestations of the epilepsy as evaluated in long-term (24 h) video-EEG recordings. RESULTS: HHs ranged in size from 0.4 to 2.6 cc, with complete lateralization in six of seven patients. Ictal manifestations showed good correlation with the lobar involvement of ictal/interictal EEGs. These manifestations suggest the existence of two types of cortical involvement, one associated with the temporal lobe, produced by hamartomas connected to the posterior hypothalamus (mamillary bodies), and the other associated with the frontal lobe, seen in lesions connecting to the middle hypothalamus. CONCLUSIONS: A consistent clinical and neurophysiologic pattern of either temporal or frontal lobe cortical secondary involvement was found in the patients of our series. It depends on whether the hamartoma connects to the mamillary bodies (temporal lobe cases) or whether it connects to the medial hypothalamus (frontal lobe cases).
- Displasia Fibrosa Crânio-Facial a Propósito de Dois Casos ClínicosPublication . Sousa, H; Ferreira, R; Baptista, S; Ribeiro, C; Sousa, V; Pinto, M; Barros, EDependendo da localização e do número de ossos envolvidos, a Displasia Fibrosa (D.F.) crânio-facial pode ser responsável por síndromes dismórficos e por sintomatologia otológica, oftalmológica ou rinológica. Este artigo tem por objectivo i1ustrar dois casos clínicos de D. F. Poliostótica com envolvimento predominante dos ossos temporal a etmóide. No primeiro caso clínico o envolvimento do osso temporal é responsável por síndrome vertiginoso resultante de hipofunção vestibular esquerda e da obliteração do aqueduto vestibular homolateral. Neste coso o doente foi submetido a neurectomia dos nervos vestibulares, por via retrosigmóide. O segundo caso clínico é um caso de D.F. predominantemente do osso etmóide, acompanhado de proptose e obstrução nasal, em que se procedeu à excisão total por via paralateronasal sob controlo endoscópico. Os autores fazem uma revisão da literatura sobre a clínica, o diagnóstico, e a terapêutica do da doença a nível crânio-facial.
- Formas Atípicas de Hipoacúsia em Doentes com o Diagnóstico de Neurinoma do AcústicoPublication . Sousa, H; Ferreira, R; Cardoso, I; Baptista, S; Ribeiro, C; Sousa, V; Marques, PA hipoacúsia neurosensorial unilateral e progressiva é uma das principais manisfestações audiológicas dos doentes com diagnóstico de neurinoma do acústico, estando no entanto descritas outras formas de apresentação. Dos 43 doentes com diagnóstico de neurinoma do acústico, tratados pela equipa de otoneurocirurgia entre 1997 e 2003, identificamos 88,5% com hipoacústica neurosensorial unilateral, 4,6% como hipoacústica neurosensorial súbita, 4,6% com audição simétrica e 2,3% com audição "normal". Estes dados revelam a existência de três formas incomuns de apresentação dos neurinomas, facto que deve levar os otorrinolaringologistas a manterem um elevado grau de alerta perante doentes com queixas que possam sugerir, de algum modo, a presença de neurinoma do acústico.
- Hematoma Laríngeo por Tosse Persistente em Doente com Hemofilia A - Caso ClínicoPublication . Montemor, R; Araújo Martins, J; Pereira, S; Ribeiro, C; Marques Pinto, L; Barros, EO hematoma laríngeo é um acontecimento raro em doentes com hemofilia A que pode causar compromisso da via aérea e está habitualmente associado a tosse persistente como resultado de uma infecção respiratória. Em caso de estabilidade clínica, o tratamento da causa subjacente, a abolição da tosse, a reposição de factores de coagulação e uma vigilância apertada são suficientes para a resolução do hematoma e normalização da via aérea, sem necessidade de entubação ou procedimento cirúrgico. Os autores apresentam um caso clínico de um doente com hematoma laríngeo por deficiência de factor VIII e presença de inibidores deste factor tratado com uma abordagem conservadora com melhoria progressiva do quadro clínico.
- Measuring Adherence to Inhaled Control Medication in Patients with Asthma: Comparison Among an Asthma App, Patient Self‐Report and Physician AssessmentPublication . Cachim, A; Pereira, AM; Almeida, R; Amaral, R; Alves‐Correia, M; Vieira‐Marques, P; Chaves‐Loureiro, C; Ribeiro, C; Cardia, F; Gomes, J; Vidal, C; Silva, E; Rocha, S; Rocha, D; Marques, ML; Páscoa, R; Morais, D; Cruz, AM; Santalha, M; Simões, JA; da Silva, S; Silva, D; Gerardo, R; Todo Bom, F; Morete, A; Vieira, I; Vieira, P; Monteiro, R; Raimundo, MR; Monteiro, L; Neves, Â; Santos, C; Penas, AM; Regadas, R; Varanda Marques, J; Rosendo, I; Abreu Aguiar, M; Fernandes, S; Seiça Cardoso, C; Pimenta, F; Meireles, P; Gonçalves, M; Almeida Fonseca, J; Jácome, CBackground: Previous studies have demonstrated the feasibility of using an asthma app to support medication management and adherence but failed to compare with other measures currently used in clinical practice. However, in a clinical setting, any additional adherence measurement must be evaluated in the context of both the patient and physician perspectives so that it can also help improve the process of shared decision making. Thus, we aimed to compare different measures of adherence to asthma control inhalers in clinical practice, namely through an app, patient self-report and physician assessment. Methods: This study is a secondary analysis of three prospective multicentre observational studies with patients (≥13 years old) with persistent asthma recruited from 61 primary and secondary care centres in Portugal. Patients were invited to use the InspirerMundi app and register their inhaled medication. Adherence was measured by the app as the number of doses taken divided by the number of doses scheduled each day and two time points were considered for analysis: 1-week and 1-month. At baseline, patients and physicians independently assessed adherence to asthma control inhalers during the previous week using a Visual Analogue Scale (VAS 0-100). Results: A total of 193 patients (72% female; median [P25-P75] age 28 [19-41] years old) were included in the analysis. Adherence measured by the app was lower (1 week: 31 [0-71]%; 1 month: 18 [0-48]%) than patient self-report (80 [60-95]) and physician assessment (82 [51-94]) (p < 0.001). A negligible non-significant correlation was found between the app and subjective measurements (ρ 0.118-0.156, p > 0.05). There was a moderate correlation between patient self-report and physician assessment (ρ = 0.596, p < 0.001). Conclusions: Adherence measured by the app was lower than that reported by the patient or the physician. This was expected as objective measurements are commonly lower than subjective evaluations, which tend to overestimate adherence. Nevertheless, the low adherence measured by the app may also be influenced by the use of the app itself and this needs to be considered in future studies.
- A Medicina Geral e Familiar e a Saúde Mental Infantil: Um Encontro NecessárioPublication . Ribeiro, C; Marques, C
- Meningioma and Breast Cancer: Survival of Patients with Synchronous and Metachronous Meningioma and Breast CancerPublication . Lavrador, JP; Valente Pinto, M; Mascarenhas Lemos, L; Ribeiro, C; Peralta Santos, AThe prognosis of the association between Breast Cancer (BC) and Meningioma (M) is unknown. To evaluate the survival impact of tumor exposure sequence in patients with both tumors. Patients were divided in groups according to the tumors sequence: BC before M (group 1), synchronous BC + M (group 2) and BC after M (group 3). The SEER database was used. Demographics, meningioma and breast cancer variables were analyzed. The primary outcome was oncological survival. A total of 1715 patients were included (median follow-up:84 months). Group 2 had the shortest survival (median:32 months) and group 1 the longest (median:110 months). On the unadjusted analysis, group 2 had the shortest survival (HR:3.13, 95% CI 1.62-6.04) and adjusted analysis confirmed this finding (HR 3.11, 95% CI 1.58-6.19), with no statistical difference between the metachronous tumors groups. Increasing age (HR:1.13, 95% CI 1.11-1.15, p < 0.005) and grade III meningioma (HR:4.51, 95% CI 1.90-10.69, p < 0.005) were related with lower survival. Meningioma treatment had no influence on the survival (p > 0.05). The association between surgery and radiotherapy in BC treatment improved the outcome (HR 0.37, 95% CI 0.23-0.93, p < 0.05). Grade III meningioma and receptor hormonal status influenced synchronous tumors (p < 0.05) but had no influence on metachronous tumors survival (p > 0.05) on stratified analysis. Synchronous tumors were associated with lower survival. Increasing age had a negative influence on patient survival. Although surgery and radiotherapy for breast cancer had a positive influence in the outcome, meningioma treatment was not related with survival. Grade III meningioma and hormonal receptor status only influenced synchronous tumors patient survival.