Browsing by Issue Date, starting with "2017-09-20"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
- Portal Vein Embolization With N-Butyl-Cyanoacrylate Through an Ipsilateral Approach Before Major Hepatectomy: Single Center Analysis of 50 Consecutive PatientsPublication . Mendes Luz, JH; Mendes Luz, P; Bilhim, T; Martin, H; Gouveia, H; Coimbra, E; Veloso Gomes, F; Souza, R; Faria, I; Nepomuceno de Miranda, TPURPOSE: To evaluate the efficacy of portal vein embolization (PVE) with n-Butyl-cyanoacrylate (NBCA) through an ipsilateral approach before major hepatectomy. Secondary end-points were PVE safety, liver resection and patient outcome. METHODS: Over a 5-year period 50 non-cirrhotic consecutive patients were included with primary or secondary liver cancer treatable by hepatectomy with a liver remnant (FLR) volume less than 25% or less than 40% in diseased livers. RESULTS: There were 37 men and 13 women with a mean age of 57 years. Colorectal liver metastases were the most frequent tumor and patients were previously exposed to chemotherapy. FLR increased from 422 ml to 629 ml (P < 0.001) after PVE, corresponding to anincrease of 52%. The FLR ratio increased from 29.6% to 42.3% (P < 0.001). Kinetic growth rate was 2.98%/week. A negative association was observed between increase in the FLR and FLR ratio and FLR volume before PVE (P = 0.002). In 31 patients hepatectomy was accomplished and only one patient presented with liver insufficiency within 30 days after surgery. CONCLUSIONS: PVE with NBCA through an ipsilateral puncture is effective before major hepatectomy. Meticulous attention is needed especially near the end of the embolization procedure to avoid complications.