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- A Case Report: Unmasking a Singular Culprit for Cardiogenic Shock: Looking Beyond the Coronary TreePublication . Morais, LM; Portugal, G; Cruz Ferreira, RBACKGROUND: Cardiogenic shock remains challenging in its therapy and aetiology. CASE SUMMARY: A 74-year-old woman admitted for cardiogenic shock requiring mechanical ventilation and high-dose inotropics and vasopressors with an electrocardiogram showing left ventricular (LV) lateral wall ischaemia had diffuse coronary artery disease but TIMI III flow in the coronary tree. An echocardiogram showed a suspicious mass invading the left ventricle and computed tomography scan revealed an advanced lung cancer with LV wall and pulmonary artery invasion as the cardiogenic shock cause. DISCUSSION: When managing cardiogenic shock, it is important to consider different and not obvious diagnosis. A high level of clinical suspicion and multimodality imaging assessment was very important in the present case to attain the diagnosis.