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Alcohol Consumption Post-Liver Transplantation: a Cross-Sectional Study

2023Journal article Open access
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dc.contributor.authorChálim Rebelo, C
dc.contributor.authorFélix, C
dc.contributor.authorSousa Cardoso, F
dc.contributor.authorBagulho, L
dc.contributor.authorSousa, M
dc.contributor.authorMendes, M
dc.contributor.authorGlória, H
dc.contributor.authorMateus, É
dc.contributor.authorMega, I
dc.contributor.authorJara, M
dc.contributor.authorPinto Marques, H
dc.contributor.authorNolasco, F
dc.contributor.authorMartins, A
dc.contributor.authorPerdigoto, R
dc.date.accessioned2023-12-12T15:32:47Z
dc.date.available2023-12-12T15:32:47Z
dc.date.issued2023
dc.description.abstractBackground: Listing patients with alcohol-associated liver disease (ALD) for liver transplant (LT) remains challenging especially due to the risk of alcohol resumption post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center. Methods: We conducted a cross-sectional study including LT recipients from 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pretested survey and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) were applied via a telephone call. Alcohol consumption was defined by patients' self-reports or a positive AUDIT. Results: In 2019, 122 patients underwent LT, and 99 patients answered the survey (June 2021). The mean (SD) age was 57 (10) years, 70 patients (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20-26) months post-index LT, 22 (22.2%) recipients consumed any amount of alcohol: 14 had a drink monthly or less and 8 drank 2-4 times/month. On drinking days, 18 patients usually consumed 1-2 drinks and the remainder no more than 3-4 drinks. One patient reported having drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low risk (score <8) as per the AUDIT score (median [IQR] of 1 [1-2]). No patient reported alcohol-related problems, whether self-inflicted or toward others. Drinking recipients were younger (53 vs. 59 years, p = 0.020), had more non-ALD-related LT (72.7 vs. 44.2%, p = 0.018) and active smoking (31.8 vs. 10.4%, p = 0.037) than abstinent ones. Conclusion: In our cohort, about a quarter of LT recipients consumed alcohol early posttransplant, all with a low-risk pattern according to the AUDIT score.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGE Port J Gastroenterol . 2022 Oct 17;30(5):343-349.pt_PT
dc.identifier.doi10.1159/000525808pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4759
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKargerpt_PT
dc.subjectHCC CHBPTpt_PT
dc.subjectAlcoholismpt_PT
dc.subjectLiver Transplantpt_PT
dc.subjectRecidivismpt_PT
dc.subjectRelapsept_PT
dc.titleAlcohol Consumption Post-Liver Transplantation: a Cross-Sectional Studypt_PT
dc.title.alternativeConsumo de Álcool Pós-Transplante hepático: um Estudo Transversalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage349pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage343pt_PT
oaire.citation.titleGE - Portuguese Journal of Gastroenterologypt_PT
oaire.citation.volume30pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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