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Body Composition Evaluation and Clinical Markers of Cardiometabolic Risk in Patients with Phenylketonuria

dc.contributor.authorLuengo-Pérez, LM
dc.contributor.authorFernández-Bueso, M
dc.contributor.authorAmbrojo, A
dc.contributor.authorGuijarro, M
dc.contributor.authorFerreira, AC
dc.contributor.authorPereira-da-Silva, L
dc.contributor.authorMoreira-Rosário, A
dc.contributor.authorFaria, A
dc.contributor.authorCalhau, C
dc.contributor.authorDaly, A
dc.contributor.authorMacDonald, A
dc.contributor.authorRocha, JC
dc.date.accessioned2024-01-17T12:07:46Z
dc.date.available2024-01-17T12:07:46Z
dc.date.issued2023
dc.description.abstractCardiovascular diseases are the main cause of mortality worldwide. Patients with phenylketonuria (PKU) may be at increased cardiovascular risk. This review provides an overview of clinical and metabolic cardiovascular risk factors, explores the connections between body composition (including fat mass and ectopic fat) and cardiovascular risk, and examines various methods for evaluating body composition. It particularly focuses on nutritional ultrasound, given its emerging availability and practical utility in clinical settings. Possible causes of increased cardiometabolic risk in PKU are also explored, including an increased intake of carbohydrates, chronic exposure to amino acids, and characteristics of microbiota. It is important to evaluate cardiovascular risk factors and body composition in patients with PKU. We suggest systematic monitoring of body composition to develop nutritional management and hydration strategies to optimize performance within the limits of nutritional therapy.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNutrients . 2023 Dec 18;15(24):5133pt_PT
dc.identifier.doi10.3390/nu15245133pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4791
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)pt_PT
dc.subjectAnthropometrypt_PT
dc.subjectBiomarkerspt_PT
dc.subjectBody Compositionpt_PT
dc.subjectBody Mass Indexpt_PT
dc.subjectCardiovascular Diseases* / etiologypt_PT
dc.subjectHumanspt_PT
dc.subjectPhenylketonurias* / complicationspt_PT
dc.subjectHDE MTBpt_PT
dc.titleBody Composition Evaluation and Clinical Markers of Cardiometabolic Risk in Patients with Phenylketonuriapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue24pt_PT
oaire.citation.startPage5133pt_PT
oaire.citation.titleNutrientspt_PT
oaire.citation.volume15pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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