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Antibiotics Utilization Ratio in a Nicu

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Abstract(s)

Introduction: Antibiotics are one of the most common prescribed drugs in the NICU; despite this, studies on its use are scarce. Aim: To assess antibiotics utilization ratio in a medical surgical NICU. Methods: Prospective, observational study. Daily registry of antibiotics given to newborn infants; two periods of two months, 2010; data collected every day after the second medical round. Variables: treated patients, days on antibiotics, treatment/patient days, number of courses, number of antibiotics. Antibiotics utilization ratio – ratio days on antibiotics/days at the NICU. Results: Patients enrolled - 113; admission days – 1722; length of stay - 15.2 days; 85 newborn infants were given antibiotics; days on antibiotics - 771; antibiotics utilization ratio – 44.8; 292 antibiotics were prescribed; 61.8% of patients were given more than two antibiotics and 15.3% had more than one course. The most frequents were gentamicin, cefotaxime, ampicillin, vancomycin and metronidazole. Conclusion: Antibiotics utilization ratio should be subject of audits and a quality criteria on NICUs evaluation.

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Keywords

Antibióticos Ratio Cuidados Intensivos Neonatais HDE UCI NEO

Citation

IN: 19th European Workshop on Neonatology; 2011, 28/9-1/10.Segóvia.

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Departamento de Pediatria e Unidade de Cuidados Intensivos Neonatais, Hospital Dona Estefânia, Cemtro Hospitalar de Lisboa Central, EPE

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