Conscious Sedation with Inhaled 50% Nitrous Oxide/Oxygen Premix in Photodynamic Therapy Sessions for Vulvar Lichen Sclerosus Treatment

Cabete, J; Lestre, S; Campos, S

http://hdl.handle.net/10400.17/2005

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Authors

Cabete, J

Lestre, S

Campos, S

Abstract(s)

Photodynamic therapy has been described as an effective therapeutic option in selected cases of anogenital lichen sclerosus that are refractory to first-line treatments. However, procedure-related pain is a limiting factor in patient adherence to treatment. The authors report the case of a 75-year-old woman with highly symptomatic vulvar lichen sclerosus, successfully treated with photodynamic therapy. An inhaled 50% nitrous oxide/oxygen premix was administered during sessions, producing a pain-relieving, anxiolytic, and sedative effect without loss of consciousness. This ready-to-use gas mixture may be a well-tolerated and accepted alternative to classical anesthetics in Photodynamic therapy, facilitating patients' adherence to illumination of pain-prone areas.

Keywords

HSAC DER Anesthetics, Inhalation/administration & dosage Conscious Sedation Nitrous Oxide/administration & dosage Oxygen/administration & dosage Photochemotherapy/methods Reproducibility of Results Time Factors Treatment Outcome Vulvar Lichen Sclerosus/drug therapy