Publication
The Utility of Apparent Diffusion Coefficient Values in the Risk Stratification of Prostate Cancer Using a 1.5 T Magnetic Resonance Imaging Without Endorectal Coil
| dc.contributor.author | Lopes Dias, J | |
| dc.contributor.author | Magalhães Pina, J | |
| dc.contributor.author | Vasco Costa, N | |
| dc.contributor.author | Carmo, S | |
| dc.contributor.author | Leal, C | |
| dc.date.accessioned | 2019-03-13T12:02:10Z | |
| dc.date.available | 2019-03-13T12:02:10Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | Purpose: To evaluate the relationship between mean apparent diffusion coefficient (ADC) and post-surgical Gleason scores. To determine the diagnostic accuracy of multiparametric magnetic resonance imaging (mp-MRI) on a 1.5 T magnet in distinguishing low, intermediate and highgrade prostate tumors. Material and methods: This is a retrospective institutional-review-board-approved, singlecenter study including 30 patients (median age, 60 years) who underwent mp-MRI before prostatectomy for prostate cancer. Using histological reports for guidance, the tumors were localized in ADC maps, and mean ADCs were measured and examined for correlation with Gleason scores. 2 patients had 2 measurable foci, so a total of 32 tumors were studied. The diagnostic accuracy of the mean ADC was assessed by using the area under the receiver operating characteristic curve (ROC). Results: In the differentiation of tumors with a Gleason score of 6 from those with a Gleason score of at least 7, mean ADC yielded an AUC of 0.76 (95% confidence interval: 0.59, 0.93). In the differentiation of tumors with Gleason scores of 6 or 7 from those with a Gleason score of at least 8, mean ADC yielded an AUC of 0.94 (95% confidence interval: 0.86, 1.00). Conclusion: Mean ADC values may allow a correct assessment of the patient risk using a 1.5 T magnet without ERC. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Acta Urol Port. 2016;33(3):81-86 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/3188 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Associação Portuguesa de Urologia | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | Multiparametric Magnetic Resonance Imaging | pt_PT |
| dc.subject | Prostate Cancer | pt_PT |
| dc.subject | Apparent Diffusion Coefficient | pt_PT |
| dc.subject | Gleason Score | pt_PT |
| dc.subject | Risk Stratification | pt_PT |
| dc.subject | HSJ IMA | pt_PT |
| dc.subject | HSJ URO | pt_PT |
| dc.title | The Utility of Apparent Diffusion Coefficient Values in the Risk Stratification of Prostate Cancer Using a 1.5 T Magnetic Resonance Imaging Without Endorectal Coil | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 86 | pt_PT |
| oaire.citation.issue | 3 | pt_PT |
| oaire.citation.startPage | 81 | pt_PT |
| oaire.citation.volume | 33 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |