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Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation

dc.contributor.authorCardoso, G
dc.contributor.authorAguiar, C
dc.contributor.authorAndrade, MJ
dc.contributor.authorPatrício, L
dc.contributor.authorFreire, I
dc.contributor.authorSerrano, F
dc.contributor.authorAnjos, R
dc.contributor.authorMendes, M
dc.date.accessioned2015-01-30T17:42:49Z
dc.date.available2015-01-30T17:42:49Z
dc.date.issued2015
dc.description.abstractINTRODUCTION: Pregnant women with mechanical prosthetic heart valves are at increased risk for valve thrombosis. Management decisions for this life-threatening complication are complex. Open-heart surgery has a very high risk of maternal mortality and fetal loss. Bleeding and embolic risks associated with thrombolytic agents, the limited efficacy of thrombolysis in certain subgroups, and a lack of experience in the setting of pregnancy raise important concerns. CASE REPORT: We report a case of mitral prosthetic valve thrombosis in early pregnancy, which was successfully treated with streptokinase. Ten years later, the same patient had an uneventful pregnancy, throughout which acenocoumarol was maintained. CONCLUSION: With this case we review the prevention (with oral anticoagulant therapy) and treatment of prosthetic valve thrombosis during pregnancy, which is important for both obstetrician and cardiologist.por
dc.identifier.citationRev Port Cardiol. 2015 Jan;34(1):71.e1-5.por
dc.identifier.urihttp://hdl.handle.net/10400.17/1994
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Cardiologiapor
dc.subjectHSM CARpor
dc.subjectMAC GINpor
dc.subjectAnticoagulants/therapeutic usepor
dc.subjectMitral Valvepor
dc.subjectPregnancy Complications, Cardiovascular/drug therapypor
dc.subjectPregnancypor
dc.subjectThrombolytic Therapy
dc.titleProsthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulationpor
dc.title.alternativeTrombose de Prótese Mitral na Gravidez: da Trombólise Até à Anticoagulaçãopor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage71.e5por
oaire.citation.startPage71.e1por
oaire.citation.titleRevista Portuguesa de Cardiologiapor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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