Repository logo
 
Publication

Sickle cell anemia - Nitric oxide related genetic modifiers of hematological and biochemical parameters

2016Journal article Open access
Simple item page
dc.contributor.authorAguiar, L
dc.contributor.authorMatos, A
dc.contributor.authorGil, A
dc.contributor.authorAfonso, C
dc.contributor.authorAlmeida, S
dc.contributor.authorBraga, L
dc.contributor.authorLavinha, J
dc.contributor.authorKjollerstrom, P
dc.contributor.authorFaustino, P
dc.contributor.authorBicho, M
dc.contributor.authorInácio, A
dc.date.accessioned2017-11-14T13:35:00Z
dc.date.available2017-11-14T13:35:00Z
dc.date.issued2016
dc.description.abstractSickle cell anemia (SCA) is an inherited blood disorder. SCA patients present clinical and hematologic variability that cannot be only explained by the single mutation in the beta-globin gene. Others genetic modifiers and environmental effects are important for the clinical phenotype. SCA patients present arginine deficiency that contributes to a lower nitric oxide (NO) bioactivity.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Hemorheol Microcirc. 2016;64(4):957-963pt_PT
dc.identifier.doi10.3233/CH-168008pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2799
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIOS Presspt_PT
dc.subjectAdolescentpt_PT
dc.subjectAdultpt_PT
dc.subjectAnemia, Sickle Cellpt_PT
dc.subjectChildpt_PT
dc.subjectChild, Preschoolpt_PT
dc.subjectFemalept_PT
dc.subjectHumanspt_PT
dc.subjectMalept_PT
dc.subjectNitric Oxidept_PT
dc.subjectPolymorphism, Geneticpt_PT
dc.subjectQuality of Lifept_PT
dc.subjectYoung Adultpt_PT
dc.subjectHDE HEM PEDpt_PT
dc.subjectHDE GENpt_PT
dc.titleSickle cell anemia - Nitric oxide related genetic modifiers of hematological and biochemical parameterspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage963pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage957pt_PT
oaire.citation.volume64pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Clin Hemorheol Microcircul 2016_957.pdf
Size:
132.18 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

HEM PED - Artigos
GEN - Artigos