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Acute Lymphoblastic Leukemia Presenting with Bilateral Serous Macular Detachment

2015Journal article Open access
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dc.contributor.authorVieira, L
dc.contributor.authorAguiar Silva, N
dc.contributor.authorDutra Medeiros, M
dc.contributor.authorFlores, R
dc.contributor.authorMaduro, V
dc.date.accessioned2017-10-24T15:21:03Z
dc.date.available2017-10-24T15:21:03Z
dc.date.issued2015
dc.description.abstractAcute lymphoblastic leukemia is a malignant hematopoietic neoplasia, which is rare in adults. Although ocular fundus alterations may be commonly observed in the course of the disease, such alterations are rarely the presenting signs of the disease. Here we describe the case of a patient with painless and progressive loss of visual acuity (right eye, 2/10; left eye, 3/10) developing over two weeks, accompanied by fever and cervical lymphadenopathy. Fundus examination showed bilateral macular serous detachment, which was confirmed by optical coherence tomography. Fluorescein angiography revealed hyperfluorescent pinpoints in the posterior poles. The limits of the macular detachment were revealed in the late phase of the angiogram. The results of blood count analysis triggered a thorough, systematic patient examination. The diagnosis of acute lymphoblastic leukemia B (CD10+) was established, and intensive systemic chemotherapy was immediately initiated. One year after the diagnosis, the patient remains in complete remission without any ophthalmologic alterations.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationArq Bras Oftalmol. 2015 Nov-Dec;78(6):382-4pt_PT
dc.identifier.doi10.5935/0004-2749.20150101pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2772
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectFemalept_PT
dc.subjectFluorescein Angiographypt_PT
dc.subjectHumanspt_PT
dc.subjectMacula Luteapt_PT
dc.subjectMiddle Agedpt_PT
dc.subjectPrecursor Cell Lymphoblastic Leukemia-Lymphomapt_PT
dc.subjectRetinal Detachmentpt_PT
dc.subjectTomography, Optical Coherencept_PT
dc.subjectTreatment Outcomept_PT
dc.subjectVisual Acuitypt_PT
dc.subjectCHLC OFTpt_PT
dc.titleAcute Lymphoblastic Leukemia Presenting with Bilateral Serous Macular Detachmentpt_PT
dc.title.alternativeLeucemia Linfoblástica Aguda com Descolamento Macular Seroso Bilateralpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage384pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage382pt_PT
oaire.citation.titleArquivos Brasileiros de Oftalmologiapt_PT
oaire.citation.volume78pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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