Publication
Idiopathic Hypocomplementaemic Tubulointerstitial Nephritis
| dc.contributor.author | Azevedo, A | |
| dc.contributor.author | Mesquita, I | |
| dc.contributor.author | Viana, H | |
| dc.contributor.author | Rocha, G | |
| dc.contributor.author | Ferreira, C | |
| dc.contributor.author | Fernandes, V | |
| dc.contributor.author | Murinello, A | |
| dc.contributor.author | Carvalho, F | |
| dc.contributor.author | Nolasco, F | |
| dc.date.accessioned | 2015-04-29T10:33:05Z | |
| dc.date.available | 2015-04-29T10:33:05Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | Background: Tubulointerstitial nephritis (TIN) is a common cause of kidney injury typically seen in association with drug exposure, infection or autoimmune diseases. However, TIN with interstitial immune complex deposition, without glomerular injury, is rarely observed. Case: We report a case of a 64-yearold Indian woman admitted for dialysis-requiring renal failure, without involvement of other organs. Urinalysis showed blood 3+ and 24h proteinuria of 1.5 g. Renal ultrasound revealed normal sized kidneys with loss of parenchymal-sinus differentiation. Laboratory tests disclosed low C3, positive ANA but negative anti-dsDNA, SSA and SSB. Serum protein electrophoresis was normal. The renal biopsy showed tubulointerstitial nephritis with positive immunoglobulin staining involving the interstitium and tubular basement membrane with glomerular sparing. The patient started prednisolone (1mg/kg/day) without recovery of the renal function. Conclusion: Idiopathic hypocomplementaemic tubulointerstitial nephritis is a rare disease with few cases described in the literature. To our knowledge this is the first case reported in Portugal. | por |
| dc.identifier.citation | Port J Nephrol Hypert 2015; 29 (1): 71-77 | por |
| dc.identifier.uri | http://hdl.handle.net/10400.17/2140 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Sociedade Portuguesa de Nefrologia | por |
| dc.subject | HCC NEF | por |
| dc.subject | HCC MED | por |
| dc.subject | Renal Failure, Chronic | por |
| dc.subject | Nephritis, Tubulointerstitial | por |
| dc.title | Idiopathic Hypocomplementaemic Tubulointerstitial Nephritis | por |
| dc.title.alternative | Nefrite Túbulo-Intersticial Hipocomplementémica Idiopática | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 77 | por |
| oaire.citation.startPage | 71 | por |
| oaire.citation.title | Portuguese Journal of Nephrology & Hypertension | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |