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The Arterial Switch Operation in Europe for Transposition of the Great Arteries: a Multi-Institutional Study from the European Congenital Heart Surgeons Association

2006Journal article Open access
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dc.contributor.authorSarris, G
dc.contributor.authorChatzis, A
dc.contributor.authorGiannopoulos, N
dc.contributor.authorKirvassilis, G
dc.contributor.authorBerggren, H
dc.contributor.authorHazekamp, M
dc.contributor.authorCarrel, T
dc.contributor.authorComas, J
dc.contributor.authorCarlo, D
dc.contributor.authorDaenen, W
dc.contributor.authorEbels, T
dc.contributor.authorFragata, J
dc.contributor.authorHraska, V
dc.contributor.authorIlyin, V
dc.contributor.authorLindberg, H
dc.contributor.authorMetras, D
dc.contributor.authorPozzi, M
dc.contributor.authorRubay, J
dc.contributor.authorSairanen, H
dc.contributor.authorStellin, G
dc.contributor.authorUrban, A
dc.contributor.authorDoorn, C
dc.contributor.authorZiemer, G
dc.date.accessioned2011-10-19T15:32:28Z
dc.date.available2011-10-19T15:32:28Z
dc.date.issued2006
dc.description.abstractOBJECTIVES: This study analyzes the results of the arterial switch operation for transposition of the great arteries in member institutions of the European Congenital Heart Surgeons Association. METHODS: The records of 613 patients who underwent primary arterial switch operations in each of 19 participating institutions in the period from January 1998 through December 2000 were reviewed retrospectively. RESULTS: A ventricular septal defect was present in 186 (30%) patients. Coronary anatomy was type A in 69% of the patients, and aortic arch pathology was present in 20% of patients with ventricular septal defect. Rashkind septostomy was performed in 75% of the patients, and 69% received prostaglandin. There were 37 hospital deaths (operative mortality, 6%), 13 (3%) for patients with an intact ventricular septum and 24 (13%) for those with a ventricular septal defect (P < .001). In 36% delayed sternal closure was performed, 8% required peritoneal dialysis, and 2% required mechanical circulatory support. Median ventilation time was 58 hours, and intensive care and hospital stay were 6 and 14 days, respectively. Although of various preoperative risk factors the presence of a ventricular septal defect, arch pathology, and coronary anomalies were univariate predictors of operative mortality, only the presence of a ventricular septal defect approached statistical significance (P = .06) on multivariable analysis. Of various operative parameters, aortic crossclamp time and delayed sternal closure were also univariate predictors; however, only the latter was an independent statistically significant predictor of death. CONCLUSIONS: Results of the procedure in European centers are compatible with those in the literature. The presence of a ventricular septal defect is the clinically most important preoperative risk factor for operative death, approaching statistical significance on multivariable analysis.por
dc.identifier.citationJ Thorac Cardiovasc Surg. 2006 Sep;132(3):633-9. Epub 2006 Aug 2por
dc.identifier.urihttp://hdl.handle.net/10400.17/416
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.subjectEuropapor
dc.subjectAnálise Multivariadapor
dc.subjectEstudos Retrospectivospor
dc.subjectTransposição dos Grandes Vasospor
dc.subjectProcedimentos Cirúrgicos Vascularespor
dc.titleThe Arterial Switch Operation in Europe for Transposition of the Great Arteries: a Multi-Institutional Study from the European Congenital Heart Surgeons Associationpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage639por
oaire.citation.startPage633por
oaire.citation.titleJournal of Thoracic and Cardiovascular Surgerypor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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