X-Linked Agammaglobulinemia (XLA):Phenotype, Diagnosis, and Therapeutic Challenges Around the World

X-linked agammaglobulinemia is an inherited immunodeficiency recognized since 1952. In spite of seven decades of experience, there is still a limited understanding of regional differences in presentation and complications. This study was designed by the Primary Immunodeficiencies Committee of the World Allergy Organization to better understand regional needs, challenges and unique patient features.

Keywords

Agammaglobulinemia Autoimmunity Chronic Lung Disease Family History Gastrointestinal Immunoglobulin Juvenile idiopathic arthritis Subcutaneous Immunoglobulin Vaccine Associated Paralytic Poliomyelitis XLA, X-Linked Agammaglobulinemia HDE PED