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Sentinel Node Total Tumour Load As a Predictive Factor for Non-Sentinel Node Status in Early Breast Cancer Patients – The porttle study

2020-03Journal article Open access
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dc.contributor.authorFougo, JL
dc.contributor.authorAmendoeira, I
dc.contributor.authorBrito, MJ
dc.contributor.authorCorreia, AP
dc.contributor.authorGonçalves, A
dc.contributor.authorHonavar, M
dc.contributor.authorMachado, A
dc.contributor.authorMagalhães, A
dc.contributor.authorMarta, S
dc.contributor.authorNogueira, M
dc.contributor.authorPeleteiro, B
dc.contributor.authorPontes, P
dc.date.accessioned2023-11-02T15:24:58Z
dc.date.available2023-11-02T15:24:58Z
dc.date.issued2020-03
dc.description.abstractOSNA is a molecular assay for the detection of sentinel node metastasis. TTL emerged as a concept that seems to accurately predict the status of the NSN. Authors tried to confirm this motion. This is a retrospective and multicentric study that analyzed 2164 patients, 579 of whom had positive SN and completion AD. Logistic regression models were performed in order to identify a suitable cutoff to identify patients who benefit from AD. Univariate and multivariate regression analysis showed a relationship between TTL>30000 and the presence of NSN metastasis (OR 2.84, CI 1.99-4.08, p < 0.001). Logistic regression indicated that the cutoff of 30000 copies/μL better discriminates patients with NSN positivity and allows wide use of these criteria. This cutoff value may safely assist clinicians and patients to decide to proceed or not with an AD.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSurg Oncol . 2020 Mar:32:108-114.pt_PT
dc.identifier.doi10.1016/j.suronc.2019.11.008pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4725
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectHCC CIRpt_PT
dc.subjectAdultpt_PT
dc.subjectAgedpt_PT
dc.subjectBreast Neoplasms / metabolismpt_PT
dc.subjectAged, 80 and overpt_PT
dc.subjectBreast Neoplasms / pathology*pt_PT
dc.subjectHumanspt_PT
dc.subjectFemalept_PT
dc.subjectBreast Neoplasms / surgerypt_PT
dc.subjectMiddle Agedpt_PT
dc.subjectCarcinoma, Ductal, Breast / metabolismpt_PT
dc.subjectCarcinoma, Ductal, Breast / secondary*pt_PT
dc.subjectCarcinoma, Ductal, Breast / surgerypt_PT
dc.subjectCarcinoma, Lobular / metabolismpt_PT
dc.subjectCarcinoma, Lobular / secondary*pt_PT
dc.subjectCarcinoma, Lobular / surgerypt_PT
dc.subjectFollow-Up Studiespt_PT
dc.subjectLymph Nodes / metabolismpt_PT
dc.subjectLymph Nodes / pathology*pt_PT
dc.subjectLymph Nodes / surgerypt_PT
dc.subjectLymphatic Metastasispt_PT
dc.subjectPrognosispt_PT
dc.subjectReceptor, ErbB-2 / metabolismpt_PT
dc.subjectReceptors, Estrogen / metabolismpt_PT
dc.subjectReceptors, Progesterone / metabolismpt_PT
dc.subjectYoung Adultpt_PT
dc.subjectSentinel Lymph Node Biopsy*pt_PT
dc.subjectRetrospective Studiespt_PT
dc.titleSentinel Node Total Tumour Load As a Predictive Factor for Non-Sentinel Node Status in Early Breast Cancer Patients – The porttle studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage114pt_PT
oaire.citation.startPage108pt_PT
oaire.citation.titleSurgical Oncologypt_PT
oaire.citation.volume32pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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