Publication
Perinatal Ischemic Stroke: a Five-Year Retrospective Study in a Level-III Maternity
| dc.contributor.author | Machado, V | |
| dc.contributor.author | Pimentel, S | |
| dc.contributor.author | Pinto, F | |
| dc.contributor.author | Nona, J | |
| dc.date.accessioned | 2015-05-29T12:15:52Z | |
| dc.date.available | 2015-05-29T12:15:52Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | Objective To study the incidence, clinical presentation, risk factors, imaging diagnosis, and clinical outcome of perinatal stroke. Methods Data was retrospectively collected from full-term newborns admitted to the neonatal unit of a level III maternity in Lisbon with cerebral stroke, from January 2007 to December 2011. Results There were 11 cases of stroke: nine were arterial ischemic stroke and two were cerebral venous sinus thrombosis. We estimated an incidence of arterial ischemic stroke of 1.6/5,000 births and of cerebral venous sinus thrombosis of 7.2/100,000 births. There were two cases of recurrent stroke. Eight patients presented with symptoms while the remaining three were asymptomatic and incidentally diagnosed. The most frequently registered symptoms (8/11) were seizures; in that, generalized clonic (3/8) and focal clonic (5/8). Strokes were more commonly left-sided (9/11), and the most affected artery was the left middle cerebral artery (8/11). Transfontanelle ultrasound was positive in most of the patients (10/11), and stroke was confirmed by cerebral magnetic resonance in all patients. Electroencephalographic recordings were carried out in five patients and were abnormal in three (focal abnormalities n=2, burst-suppression pattern n=1). Eight patients had previously identified risk factors for neonatal stroke which included obstetric and neonatal causes. Ten patients were followed up at outpatients setting; four patients developed motor deficits and one presented with epilepsy. Conclusions Although a modest and heterogeneous sample, this study emphasizes the need for a high level of suspicion when it comes to neonatal stroke, primarily in the presence of risk factors. The prevalence of neurological sequelae in our series supports the need of long-term follow-up and early intervention strategies. | por |
| dc.identifier.citation | Einstein (Sao Paulo). 2015 Jan-Mar;13(1):65-71 | por |
| dc.identifier.uri | http://hdl.handle.net/10400.17/2217 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Scielo | por |
| dc.subject | MAC PED | por |
| dc.subject | Brain Ischemia/diagnosis | por |
| dc.subject | Age Factors | por |
| dc.subject | Risk Factors | por |
| dc.subject | Brain Ischemia/epidemiology | por |
| dc.subject | Retrospective Studies | por |
| dc.subject | Brain Ischemia/etiology | |
| dc.subject | Brazil/epidemiology | |
| dc.subject | Echoencephalography | |
| dc.subject | Electroencephalography | |
| dc.subject | Follow-Up Studies | |
| dc.subject | Infant, Newborn | |
| dc.subject | Magnetic Resonance Imaging | |
| dc.subject | Stroke/diagnosis | |
| dc.subject | Stroke/epidemiology | |
| dc.subject | Stroke/etiology | |
| dc.subject | Time Factors | |
| dc.title | Perinatal Ischemic Stroke: a Five-Year Retrospective Study in a Level-III Maternity | por |
| dc.title.alternative | Acidente Vascular Cerebral Isquémico Perinatal: Estudo Retrospectivo de 5 Anos em Maternidade Nível III | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 71 | por |
| oaire.citation.startPage | 65 | por |
| oaire.citation.title | Einstein | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |