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First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature

dc.contributor.authorMoura, M
dc.contributor.authorSilva-Dos-Santos, A
dc.contributor.authorAfonso, J
dc.contributor.authorTalina, M
dc.date.accessioned2017-01-11T10:21:49Z
dc.date.available2017-01-11T10:21:49Z
dc.date.issued2016-07-29
dc.description.abstractAnti-NMDA receptor encephalitis is an autoimmune disease that was identified in 2007, and manifests in a stepwise manner with psychiatric, neurological and autonomic symptoms. The disease is caused by autoantibodies against NMDA receptors. It can have a paraneoplastic origin, mainly secondary to ovarian teratomas, but it can also be unrelated to the tumor. This disease can affect both sexes and all ages. CASE PRESENTATION: Here, we present a case of a 15 year-old female adolescent with first-episode psychosis with anti-NMDA receptor encephalitis not related to tumor, which manifested with delusion, hallucinations, panic attacks, agitation, and neurological symptoms, and later with autonomic instability. She was treated with immunotherapy and psychiatric medication resulting in improvement of her main psychiatric and neurological symptoms. CONCLUSION: Our main objective in presenting this case is to alert clinicians to this challenging and recent disease that has a clinical presentation that might resemble a functional psychiatric condition and can be underdiagnosed in the context of child and adolescent psychiatry.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBMC Res Notes. 2016 Jul 29;9:374pt_PT
dc.identifier.doi10.1186/s13104-016-2180-6pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2604
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBioMed Centralpt_PT
dc.subjectAnti-NMDA receptor encephalitispt_PT
dc.subjectFirst-episode psychosispt_PT
dc.subjectPsychosispt_PT
dc.subjectAdolescentpt_PT
dc.subjectCase Reportpt_PT
dc.subjectHDE PEDOPpt_PT
dc.titleFirst-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literaturept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.startPage374pt_PT
oaire.citation.volume9pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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