Leg Ulcers in Antiphospholipid Syndrome Secondary to Systemic Lupus Erythematosus Treated with Intravenous Immunoglobulin

Santos, G; João, A; Sousa, L

http://hdl.handle.net/10400.17/2109

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Authors

Santos, G

João, A

Sousa, L

Abstract(s)

BACKGROUND: Despite encouraging reports on the efficacy of intravenous immunoglobulin (IVIg) in antiphospholipid syndrome, the clinical value of this treatment is not well established, and most of the data are based on case reports and small series of patients. OBSERVATION: We describe the significant improvement of leg ulcers with IVIg in a 61-year-old female, with diabetes mellitus, venous peripherical insufficiency and secondary antiphospholipid syndrome to systemic lupus erythematosus. CONCLUSIONS: This case illustrates a rare cause of leg ulcers and documents that IVIg may be an effective adjuvant treatment in the management of selected patients with antiphospholipid syndrome when conventional strategies using subcutaneous heparin and low-dose aspirin are insufficient.

Keywords

HSAC DER Antiphospholipid Syndrome Intravenous Immunoglobulin Lupus Ulcer

URI

http://hdl.handle.net/10400.17/2109

Citation

J Dermatol Case Rep. 2014 Jun 30;8(2):38-41

Publisher

Pubmed Central

Collections

DER - Artigos

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