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Leg Ulcers in Antiphospholipid Syndrome Secondary to Systemic Lupus Erythematosus Treated with Intravenous Immunoglobulin

dc.contributor.authorSantos, G
dc.contributor.authorJoão, A
dc.contributor.authorSousa, L
dc.date.accessioned2015-04-17T16:00:29Z
dc.date.available2015-04-17T16:00:29Z
dc.date.issued2014
dc.description.abstractBACKGROUND: Despite encouraging reports on the efficacy of intravenous immunoglobulin (IVIg) in antiphospholipid syndrome, the clinical value of this treatment is not well established, and most of the data are based on case reports and small series of patients. OBSERVATION: We describe the significant improvement of leg ulcers with IVIg in a 61-year-old female, with diabetes mellitus, venous peripherical insufficiency and secondary antiphospholipid syndrome to systemic lupus erythematosus. CONCLUSIONS: This case illustrates a rare cause of leg ulcers and documents that IVIg may be an effective adjuvant treatment in the management of selected patients with antiphospholipid syndrome when conventional strategies using subcutaneous heparin and low-dose aspirin are insufficient.por
dc.identifier.citationJ Dermatol Case Rep. 2014 Jun 30;8(2):38-41por
dc.identifier.urihttp://hdl.handle.net/10400.17/2109
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherPubmed Centralpor
dc.subjectHSAC DERpor
dc.subjectAntiphospholipid Syndromepor
dc.subjectIntravenous Immunoglobulinpor
dc.subjectLupuspor
dc.subjectUlcerpor
dc.titleLeg Ulcers in Antiphospholipid Syndrome Secondary to Systemic Lupus Erythematosus Treated with Intravenous Immunoglobulinpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage41por
oaire.citation.startPage38por
oaire.citation.titleJournal of Dermatological Case Reportspor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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