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Orbital Metastasis from an Occult Breast Carcinoma (T0, N1, M1)

2018-04Journal article Open access
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dc.contributor.authorPinto Proença, R
dc.contributor.authorFernandes, J
dc.contributor.authorBurnier, M
dc.contributor.authorProença, R
dc.date.accessioned2023-03-01T12:31:19Z
dc.date.available2023-03-01T12:31:19Z
dc.date.issued2018-04
dc.description.abstractThe authors report a case of an orbital metastasis from an occult breast carcinoma. A 66-year-old woman presented with a growing left orbital tumour. Orbital CT scan was consistent with lymphoma. However, ocular pathology revealed small neoplastic cells showing an 'indian file pattern' suggestive of metastatic carcinoma and immunohistochemistry was positive for CK7, CK CAM5.2 and oestrogen receptor. A systemic evaluation was then performed with mammogram, breast ultrasound and MRI considered normal. An exhaustive systemic evaluation revealed multiple bone lesions, a right axillary lymph node lesion, which presented the same pattern on pathology and immunohistochemistry, with no evidence of a primary tumour. A diagnosis of a metastatic lobular carcinoma of the breast (T0, N1, M1) was made and the patient was started on chemotherapy and adjuvant hormonal therapy.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBMJ Case Rep . 2018 Apr 11;2018:bcr2017223542.pt_PT
dc.identifier.doi10.1136/bcr-2017-223542pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4429
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJpt_PT
dc.subjectCHLC OFTpt_PT
dc.subjectAgedpt_PT
dc.subjectFemalept_PT
dc.subjectHumanspt_PT
dc.subjectBiomarkers, Tumorpt_PT
dc.subjectBiopsypt_PT
dc.subjectBreast Neoplasms / diagnostic imagingpt_PT
dc.subjectBreast Neoplasms / pathology*pt_PT
dc.subjectCarcinoma, Lobular / diagnostic imagingpt_PT
dc.subjectCarcinoma, Lobular / secondary*pt_PT
dc.subjectCombined Modality Therapypt_PT
dc.subjectEye Neoplasms / diagnostic imagingpt_PT
dc.subjectEye Neoplasms / pathologypt_PT
dc.subjectEye Neoplasms / secondary*pt_PT
dc.subjectEye Neoplasms / therapypt_PT
dc.subjectKeratin-7 / analysispt_PT
dc.subjectMagnetic Resonance Imagingpt_PT
dc.subjectMammographypt_PT
dc.subjectNeoplasms, Unknown Primary / diagnostic imagingpt_PT
dc.subjectNeoplasms, Unknown Primary / pathology*pt_PT
dc.subjectNeoplasms, Unknown Primary / therapypt_PT
dc.subjectTomography, X-Ray Computedpt_PT
dc.subjectUltrasonographypt_PT
dc.subjectWhole Body Imagingpt_PT
dc.titleOrbital Metastasis from an Occult Breast Carcinoma (T0, N1, M1)pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPagebcr-2017-223542pt_PT
oaire.citation.titleBMJ Case Reportspt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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